There are many examples of this type of interaction. Below, we’ll review five drug-drug interactions worth knowing about. 1. Fluconazole and simvastatin Fluconazole(Diflucan) stops certain CYP450 enzymes from working properly. This change meansfluconazole interactionsare common. As an example, flucon...
药物相互作用(DDI)指一种药物的效应受到另一种药物、食物或者环境的影响而发生改变的现象。在临床工作中,通常指一种药物的药代动力学或药效动力学被另一种药物改变。因药物相互作用而被召回的上市新药,已经有多个先例(如2001年因DDI引起横纹肌溶解的降脂药西立伐他汀、2000年出现尖端扭转型室速的胃药西沙比利等),...
相关概念相互作用对(interactionpair)能够引起药物效应变化的两个药物目标药物(objectdrug,orindexdrug)在联合用药中，药效发生变化的药物相互作用药物，促发药物(interactiondrug,orprecipitatingdrug)在联合用药中，引起其他药物发生变化的药物 2药物相互作用的研究对象 药物在体外和药物在体内的相互作用药物...
药物相互作用DRUG-DRUG INTERACTION.ppt,个体预测法 给药次序 先使用相互作用药(precipitating drug)待病情稳定后,给予目标药(index drug) ,除非停用相互作用药,否则不会出现相互作用 例如西咪替丁和香豆素类的相互作用 个体预 测 疗程 相互作用的发生时间长短不一致
Drug-Drug Interaction (DDI)acute hepatic porphyria (AHP)acute intermittent porphyria (AIP)delta aminolevulinic acid synthase 1 (ALAS1)hemeThe evaluation and management of combination drug therapy assumes much importance especially where the drugs are used for prolonged time-period. Management of HIV/...
Drug-drug interactions:This is the most common type of drug interaction and involves one drug interacting with another. If you take many medicines, your chances for this type of interaction increases. For example, taking two medicines that cause drowsiness at the same time can increase this side...
An example of a minor interaction is that which occurs between hydralazine and furosemide. The pharmacologic effects of furosemide may be enhanced by concomitant administration of hydralazine, but generally not to a clinically significant degree (9). While minor drug interactions can generally be ...
drug interaction 英[drʌɡ ˌɪntərˈækʃən] 美[drʌɡ ˌɪntɚˈækʃən] 药物相互作用 [例句]Conclusion : clindamycin should be used rationally and carefully , drug interaction that may induce severe adrs should be considered.结论重视克林霉素的合理用药,警惕临床...
The drug interaction betweenwarfarinandvitamin K-containing products is a good example of this type of interaction. Warfarin acts by reducing the concentration of the active form of vitamin K in the body. Therefore, when vitamin K is taken, it reduces the effectiveness of warfarin. ...
Drug Interaction Facts, Drug-Reax, Lexi-Interact, Pharmavista, Stockley’s Drug Interactions, The Medical Letter and Vidal ,常用于处方 (用 药医嘱)的检查,以发现最具临床相关性的DDI Drug-Reax (Micromedex®) Lexi-Interact Pharmavista 信息系统识别DDI 此外,一些其它的数据库也列出了已知的DDI,包括:Da...