Drug-food/drink interaction. This is when something you eat or drink affects a drug. For instance, it can be dangerous to drink alcohol while you're on certain medications. Some vitamins and dietary supplements interact with medicines, too. Drug-condition interaction. This is when you have a...
The net result of a drug interaction may be: enhancement of effects of one or other drug (hence increasing the risk of an ADR occurring); development of totally new effects not seen when either drug is used alone; inhibition of effect of one drug by another; no change in the net result...
Use our drug interaction checker to quickly identify multi-drug interactions, including with alcohol, food, supplements, and diseases.
the colon, stimulating CD8+T cells and Th1 cells, thus enhancing the infiltration of interferon (IFN)-γ-producing γδT cells into tumors.238The interaction between IVDR of CTX and the microbiota is complex, as CTX affects the intestinal barrier integrity, resulting in the translocation of path...
We introduce the precise definition of an interaction similarity in the Method section. Fig. 2: Examples of interaction-aware conditioned ligand elaboration. a Initial core structures and binding pocket surfaces marked with given interaction conditions. Although an interaction condition is defined at an...
sensitive substrate should be used (e.g., midazolam for CYP3A). If no drug interaction is observed in the most favorable condition, then no more study is required. However, a more extensive study with different inhibitors/inducer or substrate should be carried on if there is some interacti...
Do not use fluoxetine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, and tranylcypromine. You must wait at least 14 days after stopping...
References Daniele Parisi, Melissa F. Adasme, Anastasia Sveshnikova, Sarah Naomi Bolz, Yves Moreau, Michael Schroeder, Drug repositioning or target repositioning: A structural perspective of drug-target-indication relationship for available repurposed drugs,Computational and Structural Biotechnology Journal, ...
A mutation that reduces relative fitness under a particular condition. Sweep A selective sweep is the reduction or elimination of variation within a population as a result of an increase in the proportion of one 'successful' variant. Minimal inhibitory concentration (MIC). The lowest concentration ...
These polymers also have acceptance for a wide range of pH and also show thermal gelation capability due to methyl–methyl group interaction, making them a good candidate for artificial tears. Generally regarded as safe (GRAS) rating by FDA, inert behavior, biocompatibility, high hydrophilic ...