as key players in cell processes ranging from RNA maturation and localization to the antiviral response in higher organisms. Penetrating insights into the metabolism and functions of such RNAs have come from the identification and study of proteins that contain the double-stranded-RNA-binding motif. ...
B. The double-stranded-RNA-binding motif: interference and much more. Nat. Rev. Mol. Cell Biol. 5, 1013–1023 (2004). Article CAS PubMed Google Scholar Gleghorn, M. L. & Maquat, L. E. ‘Black sheep’ that don’t leave the double-stranded RNA-binding domain fold. Trends Biochem...
(2004) The double-stranded-RNA-binding motif: interfer- ence and much more. Nat. Rev. Mol. Cell Biol. 5, 1013-1023.Tian, B., P.C. Bevilacqua, A. Diegelman-Parente, and M.B. Mathews. 2004. The double-stranded-RNA-binding motif: interference and much more. Nat. Rev. Mol. Cell ...
RNA–protein interactions Kathleen BHall, inCurrent Opinion in Structural Biology, 2002 Double stranded RNA binding domains There is currently one commonprotein domainthat is responsible for bindingRNAduplexes. Thisdouble stranded RNAbinding motif (dsRBM) is a small ∼70amino acidglobular ...
The double-stranded RNA-binding motif (dsRBM) is found in a diverse array of proteins that regulate gene expression in many organisms. We surveyed all known and predicted protein sequences from several organisms for the presence of the dsRBM. Among the major taxa sampled, only archebacteria la...
RNA-binding proteins compose a diverse group of proteins that participate in a wide range of biochemical functions (1). A subset of these proteins preferentially recognizes and binds dsRNA.1 These dsRNA-binding proteins (DSRBP) feature the presence of one or more double-stranded RNA binding ...
Double-stranded RNA Double-Stranded RNA Adenosine Deaminase Double-Stranded RNA-Binding Domain Double-Stranded RNA-Binding Motif Double-Stranded RNA-Specific Adenosine Deaminase double-stream amplifier double-strength glass double-strike double-stroke ruffs double-stroke ruffs double-stroke ruffs Double-struck...
上海玉博生物科技有限公司 主要致力于“Anti-PKR(double-stranded RNA-dependent Protein Kinase) 蛋白激酶R/双链RNA依赖蛋白激酶抗体 yb-1493R”的生产销售。多年的“Anti-PKR(double-stranded RNA-dependent Protein Kinase) 蛋白激酶R/双链RNA依赖蛋白激酶抗体 yb-149
双链RNA 1. RNA interference(RNAi) refers to the process where by double-stranded RNA(dsRNA) induces sequence-specific post-transcriptional gene silencing(PTGS). RNA干扰(RNA i)是由双链RNA(doub le-stranded RNA,dsRNA)介导的、序列特异的转录后基因沉默机制,是一古老的细胞反应通路,其在抵抗病毒感染、...
A process is provided of introducing an RNA into a living cell to inhibit gene expression of a target gene in that cell. The process may be practiced ex vivo or in vivo. The RNA has a region with double-stranded structure. Inhibition is sequence-specific in that the nucleotide sequences ...