Oral bioavailability of rifampicin, isoniazid, ethambutol, and pyrazinamide in a 4-drug fixed-dose combination compared with the separate formulations in healthy Chinese male volunteers. Clinical therapeutics 35, 161-168, doi:10.1016/j. clinthera.2013.01.003 (2013)....
Daily rifampicin in a single dose of 600 mg, combined with other drugs, usually streptomycin and isoniazid, was given to 49 patients for three months. It was planned to continue for another 15 months with twice-weekly rifampicin 1,200 mg plus isoniazid 900 mg, but the high incidence of sid...
The objective of this study is to evaluate the safety, efficacy, and appropriate dosing of a 4-month regimen of QBS in combination with delamanid and bedaquiline in participants with drug-susceptible pulmonary TB in comparison with the 6-month standard treatment (i.e., rifampicin, isoniazid, ...
摘要:Isoniazid, pyrazinamide 和 rifampicin 有 hepatotoxic 潜力,可能导致这样的 相关内容 a参与机制不完善,参与水平不高。 The participation mechanism is imperfect, the participation level is not high.[translate] ait is ideal to conduct . 举办是理想的。[translate] ...
Fixed-dose combined antituberculous (TB) agents contain rifampicin 150 mg, isoniazid 75 mg, pyrazinamide 400 mg and Ethambutol 275 mg per caplet. The fixed-dose combination drugs were obtained from Direct Observed Treatment (DOT) Clinic in Lagos University Teaching Hospital, Lagos-Nigeria....
Fourie PB, Pillai C, Mcllleron H, et al. Model Protocol: establishing the bioequivalence of rifampicin in fixed-dose formulations containing isoniazid with or without pyrazinamide and/or ethambutol compared to the single drug reference preparations administeed in loose combination. Geneva: World Health...
Ascorbic acid improves stability and pharmacokinetics of rifampicin in the presence of isoniazid. J Pharm Biomed Anal 2014;100:103–08.10.1016/j.jpba.2014.07.027Search in Google Scholar PubMed 13. Ochiai A, Ohkuma M, Danjo K. Investigation of surfactants suitable for stabilizing of latanoprost....
(Synercid), chloramphenicol, ethambutol, pyrazinamid, terizidon, dapson, prothionamid, fosfomycin, fucidinic acid, rifampicin, isoniazid, cycloserine, terizidone, ansamycin, lysostaphin, iclaprim, mirocin B17, clerocidin, filgrastim, and pentamidine; antivirals, including aciclovir, ganciclovir, bir...
Pharmacokinetic data on high-dose isoniazid for the treatment of rifampicin-/multidrug-resistant tuberculosis (RR/MDR-TB) are limited. We aimed to describe the pharmacokinetics of high-dose isoniazid, estimate exposure target attainment, identify predictors of exposures, and explore exposure–response ...
Objective: There is considerable uncertainty regarding the optimal use of rifampicin for the treatment of tuberculous (TB) meningitis. A pharmacokinetic modeling and simulation study of rifampicin concentrations in cerebrospinal fluid (C... A Mezochow,KT Thakur,I Zentner,... - 《International Journal...