Tuberculosis (TB) is a global issue, and INH was first reported to be effective for the treatment of TB in 19529. INH remains the first-line drug approved for TB therapy due to its high efficacy. The standard therapies for TB include a combination treatment of INH, rifampicin, pyrazinamide...
Objective: Develop a child-friendly Fixed Dose Combination (FDC) water-dispersible tablet for Tuberculosis (TB) treatment, with 50, 150, and 75 mg of isoniazid, pyrazinamide and rifampicin respectively. This new formulation must contain the lowest number of excipients accepted for pediatrics and ...