The article focuses on a study about the beneficial effects of an ultra-low-dose of continuous combined estradiol plus norethisterone acetate (E2/NETA) to postmenopausal women. Results show that the combination therapy can serve as a hormone-replacement therapy (HRT) option for such women. The ...
1 yr postmenopausal were randomly assigned to 12-month double-blind therapy with levormeloxifene [1.25 (n = 51), 5, 10, or 20 mg/day], low dose continuous combined hormone replacement therapy [HRT; 1 mg 17β-estradiol and 0.5 mg norethisterone acetate/day], or placebo (all n = 50)...
Ultra-low-dose estradiol/norethisterone beneficial as HRTInpharma Weekly -doi:10.2165/00128413-200816300-00043NoneSpringer International PublishingInpharma Weekly
of a continuous combined HRT containing 1 mg oestradiol and 0*5 mg norethisterone or matching placebo.DESIGN Double-blind, randomized placebo-controlled trial.PATIENTS Fifty women with type 2 diabetes.MEASUREMENTS Classical and novel risk factors for vascular disease.RESULTS Triglyceride concentra...
of continuous oral 17beta oestradiol (1 mg) and norethisterone (0.5 mg) in postmenopausal women with type 2 diabetes.Double-blind, randomized placebo-controlled trial.Hyperinsulinaemic isoglycaemic clamp and cardiovascular risk factors were assessed before and after 3 months of treatment.Twenty-eight...
Any benefits of HRT on endothelial function in this group are of particular interest. Objectives We assessed effects on vascular function of oral 17尾 oestradiol (1 mg) and norethisterone (0.5 mg) in postmenopausal women with T2DM. Design Double-blind, randomised, placebo-controlled trial. ...
Conclusions: The outcomes of the presented study suggest that HRT with low dose continuous combined HRT containing 1 mg micronized 17尾-estradiol and 0.5 mg norethisterone acetate have divergent effects on studied parameters of vascular inflammation. These effects are similar to effects of other ...
Methods: Fifty normal postmenopausal women were recruited and randomly treated with LD-HRT, 17尾-estradiol (1 mg/day) and norethisterone acetate (0.5 mg/day) (LD-HRT) or calcium supplement (controls). No significant differences in age, age at menopause, the presence of chronic diseases and ...
Bleeding pattern, efficacy and acceptance of low dose continuous combined HRT with estradiol/norethisterone acetate switching directly from oral contraceptionThere is increasing evidence that adding progestogens to estrogen replacement therapy may do more harm than good; however, whether all progestogens ...