When ingested,norethisteroneis rapidly absorbed and achieves maximum serum concentration within 1–4 h. Its oral bioavailability ranges from 47 to 73% (mean 64%). With a volume of distribution of 4 l kg−1,norethisteroneis bound to sex hormone-binding globulin (SHBG) and albumin 36% and 61...
(PRL) were measured in intervals of 2–17 days.Even though the estradiol mean values remained constant in the range of 65–115 pg throughout the period under observation, the LH mean levels increased continuously from 8 to a maximum of 23.9 mU/ml, and the FSH mean level from a pre-...
Compared to the women of the three other groups, they exhibited, in their pretreatment cycle, a diminished progesterone maximum together with a prolonged follicular phase and shortened luteal phase. On the other hand, the 17 women of group D showed a shorter follicular phase and longer luteal ...