Effects on behavior of acute and chronic intracerebral instillation of dopamine agonistsSeveral hypotheses relating dopamine system mechanisms to the behavioral effects of dopamine agonists and antagonists have been proposed for experimental models of clinical disease ranging from dyskinesia to psychosis. Most...
Molander, L, Randrup, A (1976) Effects of thymoleptics on behavior associated with changes in brain dopamine. Modification and potentiation of apomorphine-induced stimulation of mice. Psychopharmacology 49: pp. 139-144Molander, L., Randrup, A.: Effects of thymoleptics on behavior associated ...
gamma-Butyrolactone (GBL) potently inhibits stereotyped behavior induced by indirect (amphetamine and methylphenidate) and direct (apomorphine) dopamine agonists. Amphetamine induces a dose-response partial reversal of the GBL effect. The GABA antagonist, bicuculline, only partially reverses the GBL inhibiti...
This complicates progress in the understanding of dopamine's role in behavioral control processes, but also provides a major problem for neuropsychiatry, where some individuals are disproportionately vulnerable to the adverse effects of dopamine-enhancing drugs on motivation and cognition. Recent progress ...
David V, Durkin TP, Cazala P. Differential effects of the dopamine D2/D3 receptor antagonist sulpiride on self-administration of morphine into the ventral tegmental area or the nucleus accumbens. Psychopharmacology (Berl) 2002;160:307–317. ...
Effects of apomorphine and amphetamine on patterns of locomotor and investigatory behavior in rats. Pharmacol Biochem Behav 28: 393–399. Article CAS PubMed Google Scholar Geyer MA, Segal DS, Mandell AJ (1972). Effect of intraventricular infusion of dopamine and norepinephrine on motor activity....
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Role of striatal acetylcholine on dopamine D1 receptor agonist-induced turning behavior in 6-hydroxydopamine lesioned rats: a microdialysis-behavioral study The effects of MK-801, a non-competitive N-methyl D-aspartate (NMDA) receptor antagonist, of quinpirole, a dopamine (DA) D2 receptor agonist...
The present study examined the effects PNU 99194A on motor and emotional behaviors in C57BL/6J mice. Motor behavior was assessed in both habituated and nonhabituated mice. Emotional behavior was assessed using the elevated plus-maze and a social context involving an isolated C57BL/6J mouse and ...
This unique neurotransmitter affects your body, brain, and behavior. Dopamine plays a role in how we feel pleasure and rewards. It's a big part of our unique human ability to think and plan. It helps us focus, work towards goals, and find things interesting. ...