Acute kidney injury was defined based on the AKIN criteria: stage 1 was defined as an increase in serum creatinine (sCr) level by 0.3 mg/dL or more and an increase of 150% to 200% of the preoperative sCr value; stage 2 was defined as an increase of 200% to 300% of the preoperative...
In healthy rats without kidney injury, a 4-week high fat/high AGE diet increased serum creatinine, suggestive of decreased GFR, which was associated with enhanced kidney CML deposition and markers of oxidative stress and inflammation [244]. In contrast, a more recently published study examining ...