As a catabolic and glucoregulatory hormone, downstream cortisol is secreted in response to physical stress and other challenges to body homeostasis [91]. In turn, the hypothalamic–pituitary–thyroid axis controls metabolic hormones that play a key role in regulating musculoskeletal health and function...
For people living with T2D, intensive lifestyle management, including increased physical activity and a hypocaloric diet alongside behaviour change, is the cornerstone of diabetes management, with the ultimate aim being to induce weight reduction of at least 15 kg which correlates to improved glucoreg...
As noted in the text, increasing data support a model of progressive β-cell dysfunction in type 1 diabetes. Meaning, from the activities of a variety of "stressors," (e.g., inflammation, glucolipotoxicity, ER stress, etc.), β-cells move from a state of normalcy to a "stressed" sta...
a. There are numerous benefits of exercise that include: Weight Management - regular exercise can help prevent weight gain and can support weight...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a...
Our results do not support the recommendation of an LCHFD for use in prediabetes; rather interventions aimed specifically at reducing obesity and improving insulin sensitivity should be pursued.References Foster GD, Wyatt HR, Hill JO, McGuckin BG, Brill C, Mohammed BS et al. A randomized ...
Plasma glucose was measured using a One-Touch FastTake glucometer (Lifescan). For glucose tolerance tests (GTTs), mice were injected intraperitoneally with 1.75 g/kg glucose following a 6 h fast. For insulin tolerance tests (ITTs), mice were injected intraperitoneally with regular human insulin...
Glucose was sampled by tail vein using an Accu-Chek Compact Plus Glucometer (Roche Diagnostics) at baseline, 15, 30, 60 and 120 min after administration. Spleen histology. After harvest and weighing, spleens were placed lengthwise in a cassette and fixed in 10% formalin for 48 h, then ...
BP, MD and ZF designed the study; BP and MD provided the financial support. ZF carried out the majority of the experimental work and data analysis, with assistance from LC and RD. ZF wrote the initial manuscript; BP and MD critically revised, commented on and edited the manuscript. Acknowle...
Glucocortcoids mediate the stress-induced extracellular accumulation of glutamate. Brain Res. 1994, 655, 251–254. [Google Scholar] [CrossRef] Marazziti, D.; Mangiapane, P.; Carbone, M.G.; Morana, F.; Arone, A.; Massa, L.; Palermo, S.; Violi, M.; Bertini, G.; Massoni, L....
these foods because there is likely to be both intra- and inter-individual variability in the experience of pleasure during the consumption of specific foods.), and we draw on conceptual and empirical work on self-determination theory [5] to support our argument. First, we overview the nature...