THP 1 monocytes (American Type Culture Collection ATCC) were maintained in Dulbecco’s Modified Eagle Medium (DMEM, Merck Millipore F1275) supplemented with 100 U/ml penicillin, 0.1 mg/ml streptomycin and 10% heat-inactivated fetal bovine serum (FBS, Gibco Cat Nr10270098) and passaged ap...
Bunce CM, French PJ, Durham J, Stockley RA, Michell RH, Brown G (1994) Indomethacin potentiates the induction of HL60 differentiation to neutrophils, by retinoic acid and granulocyte colony-stimulating factor, and to monocytes, by vitamin D3. Leukemia 8(4): 595–604. Burnett AK, Russell ...
monocytes,BMDMs),即F4/80 + CD11b + 细胞及其相关产物在肿瘤细胞的生长 与转移过程中发挥着重要的作用,但其活化机制及产生促瘤功能的机理至今尚不 清楚。 在此研究中,我们首先发现与肿瘤细胞相互作用后的巨噬细胞可促进肿瘤细 胞的生长,且其促进肿瘤生长的功能并不依赖于巨噬细胞与肿瘤细胞间的相互接 ...
11 weeks after HSC engraftment, a significant increase in human total myeloid cells (CD33+), granulocytes (CD66b+), and monocytes (CD14+) in peripheral blood in comparison to NOG mice could be detected. Moreover, Ito and colleagues identified human eosinophils, basophils, neutrophils, and mast...
In our experience, alkaline phosphatase (ALP) is expressed in immature canine monocytes. We hypothesized that ALP is a useful marker for monocytic AML. OBJECTIVES: The objective was to compare ALP expression in neoplastic cells from dogs with lymphoma, chronic lymphocytic leukemia (CLL), acute ...
Cancer-associated fibroblasts (CAFs) are activated fibroblasts in the tumor microenvironment. They are one of the most prominent cell types in the stroma and produce large amounts of extracellular matrix molecules, chemokines, cytokines and growth factors. Importantly, CAFs promote cancer progression and...
Genista mice in that it did not contain atypical CD11b + Ly-6G int cells (Fig. 1C). Genista mice showed a slight increase in the num- ber of Ly-6C high and Ly-6C low blood monocytes (Fig. 1A and B and data not shown). A similar trend has been reported for Gfi1 ...
In our experience, alkaline phosphatase (ALP) is expressed in immature canine monocytes. We hypothesized that ALP is a useful marker for monocytic AML.ObjectivesThe objective was to compare ALP expression in neoplastic cells from dogs with lymphoma, chronic lymphocytic leukemia (CLL), acute lymphoid...
P. et al. An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation. Blood 116, 3955–3963 (2010). Article CAS PubMed Google Scholar DeNardo, D. G. et al. Leukocyte...
Histamine regulates the differentiation of CD11b+Gr-1+ IMCs ☆ Histamine promotes the differentiation of CD11b+Gr-1+ IMCs and CD11b+Ly6C+ monocytes through H1R and H2R autocrine and paracrine pathways. e f g ☆ Hdc+ IMCs are activated and recruited to colon tumors (a) Left, immunofluorescen...