“Does this have anything to do with fatal familial insomnia?” —¿Tiene esto algo que ver con el insomnio familiar fatal? Literature Digging and hunting doesn’t have anything to do with drawing down the moon!” ¡Cazar y recolectar no tiene nada que ver con invocar la luna!
However, the situation of microglia in other genetic prion diseases such as fatal familial insomnia (FFI) and familial CJD remains less understood."genomics & genetics weekly
a事实上,一个也没有 In fact, also does not have[translate] aMembers of the TSE family include (1) the diseases that afflict humans: kuru, Gertsmann-Sträussler-Scheinker (GSS), fatal familial insomnia (FFI), and Creutzfeldt-Jakob disease (CJD); and (2) the diseases that afflict animals...
Several terms have been used differently across theories. When possible, use of the terms was consistent with each theory. For example, IPTS distinguishes passive suicidal ideation (e.g., I wish I was dead) from active suicidal ideation (e.g., I want to kill myself) and intent (e.g.,...
Suicide is a leading cause of death among adolescents, and recent suicide theories have sought to clarify the factors that facilitate the transition from suicide ideation to action. Specifically, the Interpersonal Theory of Suicide (IPTS), Integrated Mot
There have been rare postmarketing reports of fatal and non-fatal hepatic failure in patients taking statins, including atorvastatin. Patients who consume substantial quantities of alcohol and/or have a history of liver disease may be at increased risk for hepatic injury [see Use in Specific ...
"People have inherent risk thresholds. When air bags were put in cars, for example, deaths did decrease, but not as much as they were predicted to. That's because people started to drive a little faster " thus keeping their overall safety risk level the same, Wilke said. Weber and ...
Epigenetic inheritance of conformationally altered or misfolded PrP causes diseases including fatal familial insomnia, and a rise in stress conditions increases the rate of occurrence of misfolding, and hence, epigenetic changes [143,144]. The transition of naive progenitor chromatin to B-cell lineage...
When caused by spontaneous prion misfolding, they lead to sporadic Creutzfeldt–Jakob disease, while mutations in the prion protein gene cause familial Creutzfeldt–Jakob disease, Gerstmann–Sträussler Scheinker syndrome, and fatal familial insomnia [276,278]. In this context, both prion and Aβ ...
(CJD1andFatalFamilialInsomnia(FFI),israre, amountingtoabout12casespermillionpeopleperyear, amongstwhich85%aresporadic.15%areinheritedand lessthan1%areinfectious.Thecellularprionprotein (PrP。1isacellsurfaeeglycosylphosphatidylinositol rGPI)一anchoredglycoproteinthatisexpressedinmany tissuesbesidesthecentralnervous...