Identification of islet autoantigens offers the possibility that antibody tests other than islet cell antibodies may be used for assessing risk of insulin-... E Bonifacio,S Genovese,S Braghi,... - 《Diabetologia》 被引量: 420发表: 1995年 Similar peptides from two beta cell autoantigens, pr...
Consistently, epithelial-neutralizing antibodies against Towne strain, harboring a mutation in PC, were 28-fold lower than those induced by natural infection [180]. To develop a live HCMV vaccine with the same safety of the Towne's one but more protective and immunogenic, four gen...
Indeed, this may explain why DO knock-out mice, which lack this selectivity for late endosomal sources of antigen, have delayed T-dependent humoral responses to exogenous model antigens and also develop responses to self antigens (e.g., antinuclear antibodies)37. Our model that DO acid ...
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When activated by antigens and helper T cells, B cells differentiate into plasma cells that secrete large amounts of antibodies [33]. These antibodies neutralize pathogens and mark them for destruction by other immune cells. B cells influence inflammation through antibody production and cytokine ...
The role of NGF in the pain development has also been demonstrated by studies evaluating the efficacy of using anti-NGF antibodies (tanezumab) for the treatment of knee and hip osteoarthritis, suggesting that NGF signalling inhibition, involving activation of TrkA and p75NTR receptors, may represent...
输血临床实验血型antigenstransfusion 临床输血学实验 TransfusionMedicine (bloodtransfusionlaboratories) 上海市第六人民医院 ShanghaiSixthPeopleHospital 输血科 TransfusionDepartment TestingSpecimenRequirement 2mlEDTAwholeblood Fillinthetubelabel(s)withname History Ancienttimes敬畏血液-生命的源泉-饮血疗法 Theperiod1500-...
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Dopamine is well recognized as a neurotransmitter in the brain, and regulates critical functions in a variety of peripheral systems. Growing research has a
In contrast to passive targeting, active targeting involves grafting the nanoparticle surface with specific targeting ligands, including antibodies, antibody fragments, peptides, aptamers and folic acid to direct the nanoparticles to the receptors or antigens expressed at the cancer cell surfaces and ...