Aβ peptides are at the root of the pathology of Alzheimer disease (AD)1, one of the devastating diseases of our increasingly ageing society. The peptides originate from the action of specific proteases, called secretases, on the amyloid precursor protein (APP) inside the membrane of neuronal...
MCV is a common human infection that can be detected by conformational capsid epitope immunoassays. Int. J. Cancer 125, 1250–1256 (2009). Article CAS PubMed PubMed Central Google Scholar Carter, J. J. et al. Association of Merkel cell polyomavirus-specific antibodies with Merkel cell ...
Miller, G. et al. Antibodies to butyrate-inducible antigens of Kaposi's sarcoma-associated herpesvirus in patients with HIV-1 infection.N. Engl. J. Med.334, 1292–1297 (1996). ArticleCASPubMedGoogle Scholar Gao, S. J. et al. Seroconversion to antibodies against Kaposi's sarcoma-associated...
gondii antibodies and behavioral problems that include rule breaking, risk taking, impulsivity, aggressiveness, and suicidal ideation (Martinez et al. 2018; Zerekidze et al. 2024). The mechanisms by which T. gondii can disturb behavior are not completely understood, although it is becoming evident...
Normally, the antibodies found in the blood are a type known as Immunoglobulin G (IgG), which are produced in the spleen and bone marrow—these antibodies protect the inside of the body. However, theantibodiesfound in the meninges were Immunoglobulin A (IgA), which are usually made in thegu...
involves creating antibodies that bind to abnormal developments in the brain (such as amyloid-β or tau), and mark them for destruction by a range of mechanisms. Immunotherapy is experiencing a surge of interest and a number of clinical trials – targeting both amyloid-β and tau – are curre...