The RIPE3b1 DNA-binding factor plays a critical role in pancreatic islet β cell-specific and glucose-regulated transcription of the insulin gene. Recently it was shown that RIPE3b1 binding activity in β-cell nuclear extracts is reduced by treatment with either calf intestinal alkaline phosphatase...
Acetylation regulates transcription factor activity at multiple levels. CREB-binding protein (CBP) possesses an intrinsic acetyltransferase activity capable of acetylating nucleosomal histones as well as several nonhistone prot... E Soutoglou,N Katrakili,I Talianidis - 《Molecular Cell》 被引量: 763...
DNA sequence analysis revealed a binding motif for octamer-binding transcription factor 1 (OCT-1) in the deleted fragment. Mutation of this OCT-1 binding motif resulted in a similar effect as the deletion experiment, i.e. it increased the basal promoter activity and abolished the response to ...
DNA sequence analysis revealed a binding motif for octamer-binding transcription factor 1 (OCT-1) in the deleted fragment. Mutation of this OCT-1 binding motif resulted in a similar effect as the deletion experiment, i.e. it increased the basal promoter activity and abolished the response to ...
The redox regulation mechanism has previously been known for a number of transcription factors such as Jun/Fos (25, 30), Myb (31, 32), NF-κB (26), and Ets-1 (33). Their DNA binding activity is greatly stimulated by sulfhydryl protecting agents such as DTT and mercaptoethanol or by ce...
The RIPE3b1 DNA binding factor plays a critical role in pancreatic islet β cell-specific and glucose-regulated transcription of the insulin gene. Recently it was shown that RIPE3b1 binding activity in β cell nuclear extracts is reduced by treatment with either calf intestinal alkaline phosphatase...
We have examined the activity of the Xenopus heat-shock transcription factor (HSF) in extracts from stressed and unstressed embryos at various stages of development using DNA mobility shift analysis. A specific interaction between HSF and a synthetic oligonucleotide corresponding to the proximal heat-sh...
来源期刊 Embo Journal 研究点推荐 transcription factor 3T3 Cells HMG box DNA binding transcriptional activity splice variants 引用走势 1995 被引量:18 0关于我们 百度学术集成海量学术资源,融合人工智能、深度学习、大数据分析等技术,为科研工作者提供全面快捷的学术服务。在这里我们保持学习的态度,不忘初心,...
Kinetics of the RNA-DNA helicase activity of Escherichia coli transcription termination factor rho. 2. Processivity, ATP consumption, and RNA binding. The RNA-binding and RNA-DNA helicase activities of the Escherichia coli transcription termination factor rho have been investigated using natural RNA mol...
FBI-1 potently represses transcription of the pCAT-ADH5 (comparelanes 1 and 2). Deletion of the entire POZ domain results in complete loss of transcription repression. Data are presented as relative CAT activity compared with the control (lane 1) and are the average of four independent assays...