organized into multiple linear chromosomes of different sizes, present a very complex and intricate framework for DNA replication regulation compared to prokaryotes. A single bidirectional replication origin is sufficient to direct all DNA synthesis in prokaryotes. In contrast, eukaryotic chromosome replicatio...
Smith, D. W. 1973. DNA synthesis in prokaryotes: replication. Prog. Biophys. Mol. Biol. 26:321-408.Smith, D. W. 1972. DNA synthesis in prokaryotes; rep- lication. Prog. Biophys. Mol. Biol. 26:321-408.Smith, D. W. 1973. DNA synthesis in prokaryotes: replication. Pp. 321–393. ...
通过该复制,侵入链3'端不断延伸,供体双链中的同源链不断被置换,D环不断增长(此种修复性DNA复制被称为“链置换DNA合成反应”[strand displacement DNA synthesis reaction](98)),在DSBR初期被RecBCD降解掉的DNA序列重新得到合成。最终,延伸的侵入3'链与(由同一DSB造成的)另一DSE中的5'链连接,从而导致Holliday...
in the same direction as the replication fork is called the leading strand. As might be expected, leading strand synthesis is continuous, or highly processive. In prokaryotes, this is catalyzed by DNA polymerase III (Table 15-2), which encircles the DNA helix and moves along the template ...
(15)Fuchs, R. P.,Fujii, S. 2013. Translesion DNA synthesis and mutagenesis in prokaryotes. Cold Spring Harb. Perspect. Biol. 5, a012682. (16)Woodgate R, Ennis DG. 1991. Levels of chromosomally encoded Umu proteins and requirements for in vivo UmuD cleavage. Mol Gen Genet 229: 10–16...
Chapter3 DNA复制 Chapter3 DNAreplication 第三章 DNA的复制 第一节 DNA复制的概况 一、GeneralrulesofbiosynthesisofNucleicAcids核酸生物合成的一般规则二、GeneralfeaturesofDNAreplicationDNA复制的基本特征(多数生物)三、GeneralmodelofDNAreplication复制的一般模型 2015-7-172 Prokaryoticchromosome原核染色体 2015-7-17...
The replication of damaged DNA templates by translesion synthesis (TLS) is associated with mutagenesis and carcinogenesis. This perspective discusses the different levels at which TLS may be controlled and proposes a model for TLS of severely helix-distorting DNA lesions that includes a decisive role ...
Translesion DNA synthesis and mutagenesis in prokaryotes. Cold Spring Harb. Perspect. Biol. 5, a012682 (2013). Article PubMed PubMed Central Google Scholar Goodman, M. F. & Woodgate, R. Translesion DNA polymerases. Cold Spring Harb. Perspect. Biol. 5, a010363 (2013). Article PubMed Pub...
•Replication:synthesisofdaughterDNAfromparentalDNA •Transcription:synthesisofRNAusingDNAasthetemplate •Translation:proteinsynthesisusingmRNAmoleculesasthetemplate •Reversetranscription:synthesisofDNAusingRNAasthetemplate DNAReplication Section1 GeneralConceptsofDNAReplication DNAreplication •Areactioninwhich...
A model to explain the cell division cycle in both prokaryotes and eukaryotes is presented. No specific 'G1 functions' take place during the G1 period, whi... Cooper,Stephen - 《Nature》 被引量: 229发表: 1979年 The cell cycle-associated protein kinase WEE1 regulates cell size in relation...