et al. Modular structure of the human lamin B2 replicator. Mol. Cell Biol. 24, 2958–2967 (2004). Article CAS PubMed PubMed Central Google Scholar Mott, M. L. & Berger, J. M. DNA replication initiation: mechanisms and regulation in bacteria. Nature Rev. Microbiol. 5, 343–354 (...
How is DNA replication different from DNA transcription? In transcription, only a single DNA strand is used as a template to create a complementary strand of mRNA. In transcription, one of the two DNA strands is copied into DNA In transcription, a ...
A protein structural domain that binds DNA and RNA, and that is found most commonly in transcription factors. It consists of a helix–turn–helix structure of 60 amino acids. GAR domain A Gly- and Arg-rich motif that adopts a repeated β-turn structure. It is found most commonly in prote...
During DNA replication, the double-stranded DNA molecule is unwound and separated by an enzyme called___,along with other replication proteins. This process begins at specific DNA sequences called the origin of replication, where the DNA strands are ...
II. They are primarily concerned with the making and breaking of phosphodiester bonds (the backbone of DNA structure). III. Enzymes used in the three processes are mostly similar/ comparable. Replication of DNA: DNA is the genetic material. When the cell divides, the daughter cells receive an...
DNA methylation of single sites within DRD4 and KLDR1 was associated with adult ADHD status, and multiple DNA methylation sites within TARBP1 were associated with ADHD symptoms in adulthood and childhood. Awaiting replication, findings of this pilot study point to TARBP1 as a new candidate gene ...
Berk AJ, Clayton DA (1974) Mechanism of mitochondrial DNA replication in mouse L-cells: asynchronous replication of strands, segregation of circular daughter molecules, aspects of topology and turnover of an initiation sequence. J Mol Biol 86: 801–824 ...
The Encyclopedia of DNA Elements (ENCODE) project has systematically mapped regions of transcription, transcription factor association, chromatin structure and histone modification. These data enabled us to assign biochemical functions for 80% of the genome, in particular outside of the well-studied ...
On the other hand, DNA transposons are simple in structure and can produce recombinant active episomes thus increasing the likelihood of successful transportation between host species [59]. Moreover, such small elements can be easily inserted into viral genomes, active circular forms could be packed...
In the absence of Mus81 endonuclease activity, DNA synthesis is slowed and replication initiation events are more frequent. In addition, Mus81-deficient cells fail to recover from exposure to low doses of replication inhibitors and cell viability is dependent on the XPF endonuclease. Despite an ...