1. Both strands of DNA serve as templates concurrently in replication excision repair mismatch repair none of these 2. Proofreading activity to maintain the fidelity of DNA synthesis occurs after the synthesis has been completed is a function of the 3'-5' exonuclease activity of the ...
Chromosome structure and chromatin organization have a big impact on origin selection and function. Replication origins are organized in clusters of consecutive origins that are synchronously activated. Abstract At each cell division in humans, 30,000–50,000 DNA replication origins are activated, and ...
Double-Helix - DNA; The structure of DNA is arranged in a double-helical structure where the two strands in the DNA...Become a member and unlock all Study Answers Try it risk-free for 30 days Try it risk-free Ask a question Our e...
The basic structure of DNA is called the double helix and consists of two nucleotide chains bonded together with hydrogen bonds. DNA is able to store...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can answer your t...
The structure of DNA differs from that of RNA in that the structure of DNA contains the sugar deoxyribose while that of RNA contains the sugar ribose...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can answer your toug...
The presence of 5mC in the genome has many effects on the DNA structure. 5mC forms a Watson-Crick base pair effectively withguanine, increasing the stability of a guanine:cytosine base pair[9]. Additionally, 5mC increases the overall size of the cytosine base and limits the accessibility of...
For example, the processes identified as being most important in bacteria and yeast—DNA replication and homologous recombination—do not account for certain key observations in mammalian cells and mice, which arguably provide the most relevant models for the mitotic instability of repeats that is ...
2010. Eukaryotic DNA replication origins: many choices for appro- priate answers. Nat. Rev. Mol. Cell Biol. 11:728-738. http://dx.doi.org/ 10.1038/nrm2976Me´chali,M. (2010) Eukaryotic DNA replication origins: many choices for appropriate answers. Nat. Rev. Mol. Cell. Biol., 11, ...
How is DNA replication different from DNA transcription? In transcription, only a single DNA strand is used as a template to create a complementary strand of mRNA. In transcription, one of the two DNA strands is copied into DNA In transcription, a ...
Antitumor therapeutic strategies that fundamentally rely on the induction of DNA damage to eradicate and inhibit the growth of cancer cells are integral approaches to cancer therapy. Although DNA-damaging therapies advance the battle with cancer, resista