Biochemical studies on the replication of the genome of the small DNA virus simian virus 40 (SV40) have resulted in the identification of a number of DNA replication proteins from human cells. One of these, Replication Protein A (RPA), was phosphorylated in a cell cycle-dependent manner, ...
相关知识点: 试题来源: 解析 A。细胞周期中,间期负责 DNA 复制。间期包括 G1 期、S 期和 G2 期,其中 S 期进行 DNA 复制。前期(B 选项)主要是染色体出现等变化。中期(C 选项)染色体排列在赤道板上。后期(D 选项)姐妹染色单体分离。反馈 收藏
1、静思笃行 持中秉正 Wuhan University The College of Life Science*大学大学WWW.SOPPT.CNContents13Initiation of DNA Replication4Elongation of DNA Replication5Finishing of DNA Replication6The Concepts of DNA Replication Enzyme and Protein Involved in Replication 2Materials And Special Constructure of DNA*...
The convergence point of growth-signalling pathways that control cell proliferation is the initiation of genome replication, the core of which is the assembly of pre-replicative complexes (pre-RCs), resulting in chromatin being ‘licensed’ for DNA replication in the subsequent S phase. The Mcm2–...
Replication copies the genetic information. A single strand of DNA serves as a template for a new strand The rules of base pairing direct replication DNA is replicated during the S (synthesis) stage of the cell cycle Each body cell gets a complete set of identical DNA ...
Replication origins in eukaryotic cells never fire more than once in a given S phase. Here, we summarize the role of cyclin–dependent kinases in limiting DNA replication origin usage to once per cell cycle in the budding yeast Saccharomyces cerevisiae. We have examined the role of different cyc...
is sufficient to direct all DNA synthesis in prokaryotes. In contrast, eukaryotic chromosome replication requires the orchestration of multiple DNA replication origins to ensure that each DNA polymer, irrespective of its size in the cell, is replicated exactly once during S phase of the cell cycle....
(2007) Cell cycle regulation of DNA replication. Annu. Rev. Genet., 41, 237-280.Sclafani, R.A. and Holzen, T.M. (2007). Cell cycle regulation of DNA replication. Annu Rev Genet 41, 237-280.Sclafani RA, Holzen TM. Cell cycle regulation of DNA replication. Annu Rev Genet. 2007;41...
What are two stages of the cell division part of the cell cycle? In what phase of mitosis does DNA synthesis occur? In what phase of the cell cycle does DNA replication occur? What is the stage of mitosis during which chromosomes condense and the mitotic spi...
The replication of the two chromosomes in the bacterium Vibrio cholerae is coordinated through the binding of initiator protein RctB to a checkpoint sequence, crtS. Here, Niault et al. study RctB binding dynamics across the V. cholerae cell cycle to shed light into the underlying mechanisms. ...