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Also DNA double-strand breaks may be repaired by an inaccurate repair process leading to mutations. In addition, a double strand break can cause rearrangements of the chromosome structure (possibly disrupting a gene, or causing a gene to come under abnormal regulatory control), and, if such a ...
2.Sun Y, Saha S, Wang W, Saha LK, Huang SN, Pommier Y. Excision repair oftopoisomerase DNA-protein crosslinks (TOP-DPC). DNA Repair (Amst). 2020May;89:102837. 3.Mckie S J , Neuman K C , Maxwell A . DNA topoisomerases: Advances inunderstanding of cellular roles and multi‐protein...
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