The objective of this review is to describe basic principles and steps in the analysis of DNA methylation sequencing data that in particular have been used for mammalian genomes, and more importantly to present and discuss the most pronounced computational pipelines that can be used to analyze such...
head CpG_context_test_data_bismark_bt2.deduplicated.txt Bismark methylation extractor version v0.19.0 SRR020138.15024317_SALK_2029:7:100:1672:902_length=86 - 1 57333019 z SRR020138.15024319_SALK_2029:7:100:1672:31_length=86 + 2 10026473 Z SRR020138.15024331_SALK_2029:7:100:1673:1282_length=...
参考文献 [1] Skvortsova K, Stirzaker C, Taberlay P. The DNA methylation landscape in cancer[J]. Essays in biochemistry, 2019, 63(6): 797-811. [2] Vaisvila R, Ponnaluri V K C, Sun Z, et al. Enzymatic methyl sequencing detects DNA methylation at single-base resolution from picograms...
参考文献 [1] Skvortsova K, Stirzaker C, Taberlay P. The DNA methylation landscape in cancer[J]. Essays in biochemistry, 2019, 63(6): 797-811. [2] Vaisvila R, Ponnaluri V K C, Sun Z, et al. Enzymatic methyl sequencing detects DNA methylation at single-base resolution from picograms...
Whole-Genome Bisulfite Sequencing of Two Distinct Interconvertible DNA Methylomes of Mouse Embryonic Stem Cells. 两种状态的小鼠胚胎干细胞的甲基化组学研究 1、背景 小鼠胚胎干细胞一般生长在含有血清的基质中,被称作血清干细胞(serum ESCs);加两种激酶抑制因子使胚胎干细胞在无血清的情况下更能保持多能性的基态...
1、Gong T, Borgard H, Zhang Z, Chen S, Gao Z, Deng Y. Analysis and Performance Assessment of the Whole Genome Bisulfite Sequencing Data Workflow: Currently Available Tools and a Practical Guide to Advance DNA Methylation Studies. Small Methods. 2022 Mar;6(3):e2101251. doi: 10.1002/smtd....
Whole-Genome Bisulfite Sequencing of Two Distinct Interconvertible DNA Methylomes of Mouse Embryonic Stem Cells. 两种状态的小鼠胚胎干细胞的甲基化组学研究 1、背景 小鼠胚胎干细胞一般生长在含有血清的基质中,被称作血清干细胞(serum ESCs);加两种激酶抑制因子使胚胎干细胞在无血清的情况下更能保持多能性的基态...
1、Gong T, Borgard H, Zhang Z, Chen S, Gao Z, Deng Y. Analysis and Performance Assessment of the Whole Genome Bisulfite Sequencing Data Workflow: Currently Available Tools and a Practical Guide to Advance DNA Methylation Studies. Small Methods. 2022 Mar;6(3):e2101251. doi: 10.1002/smtd....
1、Gong T, Borgard H, Zhang Z, Chen S, Gao Z, Deng Y. Analysis and Performance Assessment of the Whole Genome Bisulfite Sequencing Data Workflow: Currently Available Tools and a Practical Guide to Advance DNA Methylation Studies. Small Methods. 2022 Mar;6(3):e2101251. doi: 10.1002/smtd....
Whole-Genome Bisulfite Sequencing of Two Distinct Interconvertible DNA Methylomes of Mouse Embryonic Stem Cells. 两种状态的小鼠胚胎干细胞的甲基化组学研究 1、背景 小鼠胚胎干细胞一般生长在含有血清的基质中,被称作血清干细胞(serum ESCs);加两种激酶抑制因子使胚胎干细胞在无血清的情况下更能保持多能性的基态...