DNA Lesson for Kids: Definition & Structure DNA Model Activities DNA Projects for High School Students DNA Sequencing: Definition, Methods & Applications DNA | Definition, Characteristics & Sequencing DNA: Chemical Structure of Nucleic Acids & Phosphodiester Bonds Deoxyribonucleic Acid | Definition, Import...
These strands have two designated ends called 5’ and 3’ (you can read that as 5 prime end and 3 prime end). These numbers indicate end-to-end chemical orientation. The numbers 5 and 3 represent the fifth and third carbon atom of the sugar ring respectively. 5’ is the end, whic...
This type of chemical DNA synthesis can also be used to create labeled oligonucleotides for nucleic acid hybridization techniques. DNA sequences can also be modified using PCR either by adding restriction sites to the ends of a DNA fragment or by introducing mutations to characterize the function ...
Book2021, Chemical Biology of the Genome Siddhartha Roy, Tapas K. Kundu Explore book V.2 Review of DNA structure V.2.1 B-DNA, major and minor grooves Double-stranded DNA can adopt different types of structures depending on the base sequence, solution conditions, and the presence of other mol...
Chemical structure drawings of four DNA bases and their modified derivatives were first converted into 10 × 10 bitmap pictures, and then flattened to obtain binary sequences with a length of 100 bits. Next, a random seed was used to generate a sequence of binary numbers of equal leng...
We wish to put forward a radically different structure for the salt of deoxyribose nucleic acid. This structure has two helical chains each coiled round the same axis (see diagram).We have made the usual chemical assumptions, namely, the each chain consists of phosphate diester groups joining β...
Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA Christine R. Laramy International Institute for Nanotechnology, Northwestern University, Evanston, IL, USA Christine R. Laramy, Matthew N. O’Brien & Chad A. Mirkin Department of Chemistry, Northwestern Univer...
1. Chemical basis of DNA replication To talk about the principle of DNA replication, we need to start with the structure of DNA. DNA is composed of deoxyribonucleotides, and its basic unit deoxyribonucleotides is composed of deoxyribose, base and phosphate groups. The phosphate end is defined...
Oligo- and poly-nucleotides: 50 years of chemical synthesis. Org. Biomol. Chem. 3, 3851–3868 (2005) Article CAS Google Scholar Ducani, C., Kaul, C., Moche, M., Shih, W. M. & Högberg, B. Enzymatic production of ‘monoclonal stoichiometric’ single-stranded DNA oligonucleotides. ...
Journal2013,Food and Chemical Toxicology HartmutJaeschke, ...AnupRamachandran 7.2DNA fragmentation Another controversial feature of apoptosis isnuclear DNAfragmentation. InternucleosomalDNA fragmentation, detectable as a DNA ladder onagarose gels(Ray et al., 1990) and DNA strand breaks detectable by the...