The RIPE3b1 DNA binding factor plays a critical role in pancreatic islet β cell-specific and glucose-regulated transcription of the insulin gene. Recently it was shown that RIPE3b1 binding activity in β cell nuclear extracts is reduced by treatment with either calf intestinal alkaline phosphatase...
ATP-dependent nucleosome disruption at aheat-shock promoter mediated by binding of GAGA transcription factor. Nature 367, 525 (1994). 17 Cote,J., Quinn, J., Workman, J. L. & Peterson, C. L. Stimulation of GAL4derivative binding to nucleosomal DNA by the yeast SWI/SNF complex. Science ...
我爱我~~哈哈 好无聊 明天又热起来了 今日主题: 说 分享51赞 大话未来吧 苍穹大仙 【生物】赤霉菌分子生物学研究进展 分享11赞 分子生物吧 泪光中企盼花开 蓝景科信DAP-seq完整技术服务实验流程和原理,多种数据分析1、DAP-seq 在基因组水平上,鉴定转录因子的结合位点(transcription factor binding sites, TFBS)...
Acetylation regulates transcription factor activity at multiple levels. CREB-binding protein (CBP) possesses an intrinsic acetyltransferase activity capable of acetylating nucleosomal histones as well as several nonhistone prot... E Soutoglou,N Katrakili,I Talianidis - 《Molecular Cell》 被引量: 763...
(编译自Burst of Brain Activity during dying could explain life passing before your eyes.Science 01 May 2023) 扫码阅读全文 04 不到1秒!数学家轻松解开由五万条蠕虫缠结而成的球 我们都知道绳子多么容易缠结,而要解开又多么困难。相比...
Integrative analysis of tissue- specific methylation and alternative splicing identifies conserved transcription factor binding motifs[J]. Nucleic Acids Res, 2013, 41 :8503-8514. [32]Siegfried Z, Cedar H. DNA methylation :A molecular lock[J]. Current Biology, 1997, 7 :305-307. [33]Weinberg ...
DNA sequence analysis revealed a binding motif for octamer-binding transcription factor 1 (OCT-1) in the deleted fragment. Mutation of this OCT-1 binding motif resulted in a similar effect as the deletion experiment, i.e. it increased the basal promoter activity and abolished the response to ...
Functional Dissection of the α and β Subunits of Transcription Factor PEBP2 and the Redox Susceptibility of Its DNA Binding Activity* Author links open overlay panelHiroshi Kagoshima ‡ ¶, Yoshiko Akamatsu § ¶, Yoshiaki Ito ¶, Katsuya Shigesada ¶Show more Add to Mendeley Share ...
In the cell, IκBα functions to retain NF-κB in the cytoplasm and inhibit its DNA binding activity. These properties are a result of the direct involvement of the nuclear localization sequences and of the DNA binding region of NF-κB in complex with IκBα. A model of the interactions...
Yeast ORC specifically binds to replication origins in an ATP dependent manner and has been shown to possess ATPase activity. CDC6/Cdc18 : An essential factor for the assembly of the pre- replicative complexes that co-operates with Cdt1 to load MCM2-7 Proteolyzed in yeasts or exported out...