DBD, DNA-binding domain; HMG, high mobility group; IHF, integration host factor; NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells; OCT-1, octamer binding transcription factor 1; TBP, TATA-box binding protein; TFIIIA, transcription factor IIIA. The HMG proteins are a di...
PROTEIN domainsPROTEIN-protein interactionsRAPID eye movement sleepThe B3 DNA-binding superfamily is a group of gene families that contain a B3 domain in their proteins. Members of this superfamily are involved in responses to stresses including salt, drought, and cold stress. The...
Formation of an ATP-DnaA-specific Initiation Complex Requires DnaA Arginine 285, a Conserved Motif in the AAA+ Protein Family * Escherichia coli DnaA protein, a member of the AAA+ superfamily, initiates replication from the chromosomal origin oriC in an ATP-dependent manner. Nucleop... H Kaw...
DNA binding refers to the process where a protein, such as AR, attaches to DNA after undergoing a significant conformational change, which is crucial for its toxic effects in certain systems. AI generated definition based on: Frontiers in Neuroendocrinology, 2011 ...
UvrD, a model for non-hexameric Superfamily 1 helicases, utilizes ATP hydrolysis to translocate stepwise along single-stranded DNA and unwind the duplex. Previous estimates of its step size have been indirect, and a consensus on its stepping mechanism is lacking. To dissect the mechanism underlying...
(DNA template in PDB: 4NLG is 5′-GAAGCCGGCGGAA-3′). In this study, the free energy of each molecule is defined as follows: ΔGbinding = Gcomplex − (Gprotein + Gligand). Here,Gcomplex,Gprotein, andGligandare the free energy of the polymerase-DNA complex, the ...
The novel human DNA helicase hFBH1 is an F-box protein We have identified a novel DNA helicase in humans that belongs to members of the superfamily I helicase and found that it contains a well conserved F-box m... TS Bae,HK Lee,J Kim,... - 《Journal of Biological Chemistry》 被引...
The Alba superfamily of chromosomal proteins appear to have originated as RNA-binding proteins and to have been recruited to chromosomes possibly only with... L Aravind,LM Iyer,V Anantharaman - 《Genome Biology》 被引量: 406发表: 2003年 Specific DNA-binding by Apicomplexan AP2 transcription fact...
酚磺乙胺7.813-500pg/mlHIF-1α|HIF1A|ARNT-interacting protein|Basic-helix-loop-helix-PAS protein MOP1|BHLHE78|Class E basic helix-loop-helix protein 78|HIF-1-alpha|HIF1-alpha|hypoxia-inducible factor 1-alpha|Member of PAS protein 1|member of PAS superfamily 1|PAS domain-containing protein...
D. DNA unwinding and protein displacement by superfamily 1 and superfamily 2 helicases. Nucleic Acids Res. 34, 4154–4159 (2006). Article CAS PubMed PubMed Central Google Scholar Rad, B. & Kowalczykowski, S. C. Efficient coupling of ATP hydrolysis to translocation by RecQ helicase. Proc....