RNA ChainofnucleotidesSinglefoldedchain Nucleotide=phosphate+sugar+nitrogen-containingbase DNAandRNAStructure DNAPurinebases Adenine(A)Guanine(G)RNA Adenine(A)Guanine(G)Pyrimidinebases Cytosine(C)Thymine(T)Cytosine(C)Uracil(U)5-carbonsugar deoxyribose OHH ribose OHOH Phosphate PO4 PO4 NucleotideChain Nu...
The inclination angles for the Z'-form DNA are similar to those for the Z-form, and the angles for Z-form RNA are somewhat smaller. The axes of inclination for guanine and cytosine are similar in all three left-handed forms. ? 1995 John Wiley & Sons, Inc....
The mechanisms by which the tumor behaviors of hepatocellular carcinoma (HCC) support growth and metastasis remain largely unknown, and it has become increasingly apparent that molecular dysregulation is of considerable importance for cellular signaling pathways. Recently, RNA-binding motif protein 47 (RBM...
. The triangle size indicates the frequency of NUMTs within each window.g,Pvalues for enrichment analysis of different genome regions (Supplementary Figs.1–3and Methods). Microsat, microsatellite; rmsk-DNA, repetitive DNA; snRNA, small nuclear RNA; srpRNA, signal recognition particle RNA; super...
Many cellular proteins have evolved to recognize and repair DNA damage. This chapter focuses primarily on two experimental models in which systems biology approaches have been applied to chart cellular responses to DNA damage. The results reveal a complex system of DNA damage response involving ...
two dna/rna sequences or (2) a protein sequence (query) to a genomic database which is composed of several sequences. both scenarios have been parallelized in the literature [ 26 , 27 ], but fine-grained parallelism applies better to the first scenario due to the amount of data and ...
The invention provides a method and kit for the separation and purification of cellular components including polar and non-polar metabolites, genomic DNA, RNA and proteins from a single biological sam
DNA microarray technology is a key element in today’s functional genomics toolbox. The power of the method lies in miniaturization, automation and parallelism permitting large-scale and genome-wide acquisition of quantitative biological information from multiple samples. DNA microarrays are currently fabr...
Flow Chart of Inclusion and Exclusion Criteria of Samples From Cohort Participants eFigure 3. Associations Between Age, DunedinPACE, Race and Ethnicity, and Sex eFigure 4. Distribution of DunedinPACE by Sociobehavioral Factors eFigure 5. Linear Regression Analyses of DunedinPACE and Sociobehavioral ...