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Nathan, Jacob Paiano, Elsa Callen, Dongpeng Wang, Kenta Shinoda, Niek van Wietmarschen, Dali Zong, Raphael Pavani & André Nussenzweig National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA Sarah E. Hill, Jennifer M. Colón-Mercado, Maia Parsadanian & Michael E. ...
Based on Mark’s findings, it appears evident, assuming this is the correct family, that Jean Garceau spent his childhood and much of his formative years at Saint-Marsault. Saint Marsault Thanks to Mark’s exhaustive work, I was able to visit Saint Marsault in the spring of 2024, and ...
Di Nicolantonio F, Vitiello PP, Marsoni S, Siena S, Tabernero J, Trusolino L, et al. Precision oncology in metastatic colorectal cancer — from biology to medicine. Vol. 18, Nature Reviews Clinical Oncology. Nature Research; 2021. p. 506–25. Keller L, Belloum Y, Wikman H, Pantel ...
DNA–protein interactions regulate critical biological processes. Identifying proteins that bind to specific, functional genomic loci is essential to understand the underlying regulatory mechanisms on a molecular level. Here we describe a co-binding-medi
Why Saint-Marsault? We will never know why Jean Garceau’s parents married in 1685 at Saint-Marsault, although the conditions at Saint Etienne might be a clue. Jean said he was their child. We know from Mark’s research that his parents had a baby in 1686, and it wasn’t Jean. We...
Laurie GrieshoberStefan GrawMatt J. BarnettGary E. GoodmanChu ChenDevin C. KoestlerCarmen J. MarsitJennifer A. DohertyCancer research
Lipid nanoparticles (LNPs) for mRNA delivery have advanced significantly, but LNP-mediated DNA delivery still faces clinical challenges. This study compared various LNP formulations for delivering DNA-encoded biologics, assessing their expression efficac
Article23 May 2024 Introduction Guanine-rich sequences of DNA can fold into tetra-stranded helical assemblies known as G-quadruplexes (G4s). These structures are implicated in a number of essential biological processes such as telomere maintenance, transcription, translation, and replication1,2,3,4...
Jacquette was married on July 2, 1685, to Pierre Garceau in Saint-Marsault, Deux-Sèvres, France, about 55 miles northwest of La Rochelle. From Filae, “Pierre Goicheau, age 33, laboureur, père Nicolas Goicheau, mère Marie Cousin; Jacquette Soulard, age 18, père Jacque Soulard, mèr...