DMSO参与的氧化反应一般需要在活化剂(E+)的辅助下进行,在活化剂的作用下,能够增强二甲亚砜中氧原子的离去能力,从而得到硫鎓阳离子。常见的活化试剂有DCC、草酰氯、乙酸酐、三氟乙酸酐、五氧化二磷、吡啶/三氧化硫络合物、乙酰氯、PDCP等,这些试剂各有其特点,可以根据反应...
蒸馏瓶悬浮在温度为18 ~ 28℃的水浴中,需要蒸发的溶剂溶解二苯甲酮(沸点306℃左右)于烧瓶中用液氮冷冻(预计-78℃以下),中间通过厚壁玻璃管通道相连接,体系全程憋压状态。 结果发现无论是NMP,还是DMSO,DMF。只需要在90 ~ 140 min内就可以完成蒸发,(通过1H NMR检测基本无溶剂残留) 但是可能这种操作的条件比较极...
Polyacrylamide [APS persulfate AMPS-DMAA BIS] PA polymer for scaleable DMSO DMF NMR RDC eval menthol hormaomycin HSQC (SVD PALES calcd dipolar couplings, appl high Mr analyte tetrasaccharide Mr = 1800)Griesinger, C
or 2-propanol (i-PrOH) to give the six-coordinate monomeric complexes Ti(O-i-Pr)Cl-3(PhCHO)L (L = DMF (3), DMSO (4), or i-PrOH (5)). In the reaction of 2 with i-PrOH, the formation of the simple adduct 5 demonstrates the preferred nature of the monomeric six-coordinate ...
利用DMSO作为氧化剂将卤代烷氧化为相应的羰基化合物的反应被称为Kornblum氧化。该反应首先进行SN2取代,产生烷氧基锍离子,然后再用碱(如三乙胺、碳酸氢钠)消除一个质子和二甲硫醚而得到醛。 总结:DMSO是最为广泛使用的亚砜之一,亚砜(S=O)中负电荷集中在氧上,具有一定的亲核...
1H NMRHammett–TaftpKa PredictionSimple empirical correlations were proposed between phenol pKa in various solvents (H2O, DMF, CH3CN, DMSO, and i-PrOH) and their chemical shifts δOH measured in DMSO-d6. The following method permits to predict pKa values for most phenols in the studied ...