细胞系名称:R26-CAG-LSL-Kras*G12C-IRES-Luc(BABL/c) 目录号:NM-YD15 Smad4-Flox/Kras-LSL-G12D/Pdx1-Cre-Tg 细胞系名称:Smad4-Flox/Kras-LSL-G12D/Pdx1-Cre-Tg 目录号:NM-YD13 MC38-hGDF15 细胞系名称:MC38-Gdf15em1(hGDF15)Smoc ...
该细胞系以其密码子13杂合KRAS突变而闻名,这是结直肠癌的共同特征,暗示其与癌细胞存活和增殖有关。此外,DLD-1在APC基因中表现出突变,导致Wnt信号通路的失调,Wnt信号通路是结直肠癌发生的关键因素。DLD-1在研究中的广泛应用为肿瘤行为、药物反应和癌症遗传学提供了有价值的见解,使其成为结直肠癌研究和治疗开发的...
Effect of Simvastatin on Cetuximab Resistance in Human Colorectal Cancer With KRAS Mutations SW48, HT29, and RKO) were used to test the effect of cetuximab, simvastatin, and cetuximab plus simvastatin on cell proliferation and apoptosis in vitro... J Lee,I Lee,B Han,... - 《Jnci Journal ...
细胞系名称:R26-CAG-LSL-Kras*G12C-IRES-Luc(BABL/c) 目录号:NM-YD15 Smad4-Flox/Kras-LSL-G12D/Pdx1-Cre-Tg 细胞系名称:Smad4-Flox/Kras-LSL-G12D/Pdx1-Cre-Tg 目录号:NM-YD13 MC38-hGDF15 细胞系名称:MC38-Gdf15em1(hGDF15)Smoc ...