Dl-3n-butylphthalide (NBP) is a novel agent and has a potential role on angiogenic activity and a good curative effect against cerebral ischemia. However, the molecular mechanism remains unclear. In order to explore the effect of NBP on the incidence and development of AD, we selected Male ...
DL-3-n-Butylphthalide (DL-NBP), a small molecular compound extracted from the seeds of Apium graveolens Linn (Chinese celery), has been shown to exert neuroprotective effects due to its anti-inflammatory, anti-oxidative and anti-apoptotic activities. DL-NBP not only protects against ischemic cere...
3.Effects of Butylphthalide on Endogenous Neural Stem Cells Proliferation in Mice with Cerebral Ischemia and Reperfusion;丁苯酞对脑缺血再灌注小鼠内源性神经干细胞增殖作用影响的研究 4)dl-3n-butylphthalide丁苯酞 1.Effect ofdl-3n-butylphthalideon the Expression of caspase-3 in the Rat Model of Focal ...
Protective Effect of Dl-3n-butylphthalide on Learning and Memory Impairment Induced by Chronic Intermittent Hypoxia-Hypercapnia Exposure Jing-jing Min1,2*, Xin-long Huo1*, ling-yun Xiang1, Yan-qing Qin1, Ke-qin Chai1, Bin Wu3, Lu Jin1 & Xiao-tong Wang1 1The Center of Neurology and ...
Keywords: 过氧化物酶体增殖活化受体γ共激活因子-1α,沉默信息调节因子2相关酶1,神经保护作用,丁苯酞,脑缺血再灌注损伤,Butylphthalide,Focal cerebral ischemia reperfuson,Silent mating type information regulation 2 homolog 1,Peroxisome proliferator-activated receptor-γ coactivator-1α,Neuroprotective effect Full...
Dl-3n-butylphthalide (NBP) has been reported to be a beneficial and promising drug for the treatment and prevention of vascular dementia (VD). NBP has been demonstrated to improve learning and memory in rats with vascular cognitive impairment by activating the silent information regulator 1/brain-...
DL3nbutylphthalide (NBP) is extracted from rapeseed and exhibits multiple neuroprotective effects, exerted by inhibiting the inflammatory process, including reducing oxidative stress, improving mitochondrial function and reducing neuronal apoptosis. The present study aimed to investigate the neuroprotective ...
Blood‐brain barrier (BBB) disruption and neuronal apoptosis are important pathophysiological processes after traumatic brain injury (TBI). In clinical stroke, Dl‐3n‐butylphthalide (Dl‐NBP) has a neuroprotective effect with anti‐inflammatory, anti‐oxidative, anti‐apoptotic and mitochondrion‐...
[Corrigendum] Dl3nbutylphthalide alleviates cognitive impairment in amyloid precursor protein/presenilin1 transgenic mice by regulating the striatalenriched protein tyrosine phosphatase/ERK/cAMPresponse elementbinding protein signaling pathwayZhao, YanYang, Wen-Qiang...
The efficacy and safety of Dl-3 n-butylphthalide on progressive cerebral infarction:A randomized controlled STROBE study. Zhang C,Zhao S,Zang Y,et al. Medicine Baltimore . 2017Zhang C, Zhao S, Zang Y, Gu F, Mao S, Feng S, et al. The efficacy and safety of Dl-3n-butylphthalide on ...