ability to 1) quickly elucidate alterations in protein expression levels, 2) detect post-translational modification and mRNA processing events, and 3) dissect molecular networks associated with drug administration or exposure to environmental factors (for example, toxins, infectious agents, or radiation)...
The cell division cycle (CDC)-2-related kinases CRK3, CRK6, and CRK12, which are cyclin-dependent kinases (CDKs) have recently been identified as plausible targets [19,20]. The overexpression of both CRK12 and the cyclin protein CYC9 have been reported to increase the resistance of L. ...