别名 [14C]-Sodium Valproate、Depakote ER、Divalproex + [13] 靶点 GABA receptor x Sodium channels 作用机制 GABA receptor激动剂(γ-氨基丁酸受体激动剂)、钠通道阻滞剂 治疗领域 神经系统疾病其他疾病 在研适应症 躁郁症偏头痛癫痫的复杂部分性发作+ [2] 非在研适应症 酒精相关疾病酗酒躁郁症1型+ [3] ...
Divalproex sodium, valproic acid (generic)-Depakote, Depakene (brand)-Valproate (common name for...Presents information on the drug, valproate manufactured by Abbott Laboratories. Generic and brand name; Common usage; Side effects; Interactions with other drugs; Common dosages....
The meaning of DIVALPROEX SODIUM is a coordination compound of valproate and valproic acid that is used especially to treat manic episodes of bipolar disorder and absence seizures of epilepsy —called also divalproex.
To assess the efficacy and safety of divalproex sodium extended-release (divalproex ER) tablets as compared with sodium valproate for treatment of seizure disorder in children, an open, prospective, switch-over trial was conducted in the outpatient department of a tertiary level teaching hospital in...
Divalproex sodium is a stable co-ordination compound comprised of sodium valproate and valproic acid in a 1:1 molar relationship and formed during the partial neutralization of valproic acid with 0.5 equivalent of sodium hydroxide. Chemically it is designated as sodium hydrogen bis(2-propylpentanoate...
英文别名:Divalproex Sodium 靶点:HDAC CAS:76584-70-8 纯度:>98% 外观:见爱必信官网 保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. 描述: Divalproex sodium consists of a compound of sodium valproate and valproic ac...
Divalproex sodium is a stable co-ordination compound comprised of sodium valproate and valproic acid in a 1:1 molar relationship and formed during the partial neutralization of valproic acid with 0.5 equivalent of sodium hydroxide. Chemically it is designated as sodium hydrogen bis(2-propylpentanoate...
In this 12-week, parallel group, multicenter trial, 120 patients were randomized to treatment with divalproex sodium delayed-release tablets or olanzapine. All subjects were hospitalized for acute mania and met DSM-IV criteria for bipolar disorder type I. Divalproex dose was initially 20 mg/kg/day...
USA; 8Advanced Clinical Research Services, Bannockburn, IL, USA The objective of this study was to evaluate the efficacy and safety of divalproex sodium extended release (divalproex ER) vs placebo in combination with olanzapine or risperidone for the treatment of acute exacerbations of schizophrenia....
• Topiramate is mainly eliminated unchanged in the urine.• Valproate is metabolized in the liver by beta and omega oxidation. • Valproate metabolites are excreted in the urine. Contraindications • No contraindications• Hypersensitivity to divalproex sodium, valproic acid, sodium valproate ...