valproic acidObjectives: To analyze, from a payer perspective, the net pharmaceutical and medical costs of prescribing divalproex sodium extended-release (DVPX-ER) versus valproic acid (VPA) in patients with bipolar disorder.doi:10.1185/030079907X210831Schumock, Glen T....
Notably, these DUET data are the first to show prospective improvements on excessive daytime sleepiness (EDS), as well as key polysomnography (PSG) outcomes of sleep disruption, among adults with narcolepsy treated with Xywav® (calcium, magnesium, potassium, and sodium oxybates) oral solution. ...
The meaning of DIVALPROEX SODIUM is a coordination compound of valproate and valproic acid that is used especially to treat manic episodes of bipolar disorder and absence seizures of epilepsy —called also divalproex.
Divalproex sodium is a stable co-ordination compound comprised of sodium valproate and valproic acid in a 1:1 molar relationship and formed during the partial neutralization of valproic acid with 0.5 equivalent of sodium hydroxide. Chemically it is designated as sodium hydrogen bis(2-propylpentanoate...
Divalproex sodium consists of a compound of sodium valproate and valproic acid in a 1:1 molar relationship in an enteric coated form. In rare cases, it is also used as a treatment for major depressive disorder, and increasingly taken long-term for prevention of both manic and depressive phases...
Depakote tablets are for oral administration. Depakote tablets are supplied in three dosage strengths containing divalproex sodium equivalent to 125 mg, 250 mg, or 500 mg of valproic acid. Inactive Ingredients Depakote tablets: cellulosic polymers, diacetylated monoglycerides, povidone, pregelatinized starc...
Pharmacokinetics and safety of extended-release divalproex sodium tablets: morning versus evening administration. There were no significant differences in the pharmacokinetic parameters (p > 0.51) and safety between groups. Diurnal variation in plasma valproic acid ... Sandeep,Dutta,C Ronald,... - Ame...
To analyze, from a payer perspective, the net pharmaceutical and medical costs of prescribing divalproex sodium extended-release (DVPX-ER) versus valproic acid (VPA) in patients with bipolar disorder.The study used a decision analytic framework to compare the total costs associated with DVPX-ER ...
To compare divalproex sodium and valproic acid for therapeutic patterns, persistence rates and predictors of hospitalization among bipolar patients on monotherapy in the Veterans Affairs (VA) healthcare system. Using VA administrative data bases, we conducted a retrospective inception cohort study of VA ...
This study was designed to determine whether the acquisition cost of valproic acid, which is lower per unit than that of divalproex sodium, actually translates into overall savings when additional costs for gastrointestinal (GI) medications, procedures, and consultations related to side effects are ...