A major post-translational modification of ER-synthesized proteins is disulfide bridge formation, which is catalyzed by the family of protein disulfide isomerases. As this covalent modification provides unique structural advantages to extracellular proteins, multiple pathways to disulfide bond formation have...
Sun, Y., Bauer, M.D., Keough, T.W., Lacey, M.P. (1996). Disulfide Bond Location in Proteins. In: Chapman, J.R. (eds) Protein and Peptide Analysis by Mass Spectrometry. Methods in Molecular Biology™, vol 61. Humana Press. https://doi.org/10.1385/0-89603-345-7:185 Download ...
Intramolecular disulphide bond arrangements in nonhomologous proteins The presence and location of intramolecular disulphide bonds are a key determinant of the structure and function of proteins. Intramolecular disulphide bon... GRS Hartig,TT Tran,ML Smythe - 《Protein Science》 被引量: 25发表: 2005年...
Disulfide Bonding in Protein Biophysics. 喜欢 0 阅读量: 19 摘要: It has been known for many decades that cell surface, soluble-secreted, and extracellular matrix proteins are generally rich in disulfide bonds, but only more recently has the functional diversity of disulfide bonding in extracellular...
二硫键交联,Disulfide Bond Cross... ... ) cross link 交联;交联键 ) disulfide bonds 二硫键 ) disulfide bond 二硫键 ... www.dictall.com|基于11个网页 2. 双硫键 成三对双硫键(disulfide bonds),此特性在AaDefA氨基酸序列上完全吻合。此外埃及斑蚊defensin的mRir.ym.edu.tw|基于10个网页 3. ...
Disulfide bond isomerization in BPTI and BPTI(G36S): An NMR study of correlated mobility in proteinsPHORBOL ESTERADRENERGIC RECEPTOR, ALPHA(1G-PROTEINRECEPTOR DESENSITIZATIONHEPATOCYTERATTwo conformational isomers were observed in the1Hnuclear magnetic resonance (NMR) spectra of the basic pancreatic ...
Elaborate electron transfer pathways have evolved Escherichia coli to promote the formation of these covalent bonds and to ensure that the correct pairs of cysteines are joined in the final folded protein. These transfers of electrons consist, in the main, of cascades of disulfide bond formation ...
We have deduced the disulfide bond linkage patterns, at very low protein levels (<0.5nmol), in two cysteine-rich polypeptide domains using a new strategy i... SF Foley,Y Sun,TS Zheng,... - 《Analytical Biochemistry》 被引量: 46发表: 2008年 Primary structure of γ-bungarotoxin, a new ...
The applications of disulfide-bond chemistry to studies of protein folding, structure, and stability are reviewed and illustrated with bovine pancreatic ribonuclease A (RNase A). After surveying the general properties and advantages of disulfide-bond studies, we illustrate the mechanism of reductive unfo...
www.nature.com/scientificreports OPEN received: 02 December 2016 accepted: 06 March 2017 Published: 04 April 2017 Disulfide Bond Formation and N-Glycosylation Modulate Protein- Protein Interactions in GPI- Transamidase (GPIT) Lina Yi1,2,3, Gunes Bozkurt1,2, Qiubai Li1,2, Stanley Lo...