Understanding Pharmacokinetics: Part 2Drug Distributiondoi:10.1097/01.NAJ.0000324383.40145.00In the second in a four-part series, the coordinator of Drug Watch provides an overview.AJN The American Journal of Nursing
Pharmacokinetics,distribution,and excretion of sodium oligomannate,a recently approved anti-Alzheimer'''s disease drug in China Pharmacokinetics,distribution,and excretion of sodium oligomannate,a recently approved anti-Alzheimer'''s disease drug in China J Lu,Q Pan,J Zhou,... - 《药物分析学报...
AM Taburet,C Tollier,C Richard - 《Clinical Pharmacokinetics》 被引量: 19发表: 1990年 [Principles of pharmacology] provide a quantitative assessment of the main processes involved in biodisposition of the drug, including absorption, distribution, metabolism, and elimination... K, Taeger - 《Ana...
Approximately 5% of sodium oligomannate penetrated the blood–CSF barrier of rats. • The absorbed drug was excreted through the kidney; unabsorbed drug was excreted in feces. Abstract The National Medical Products Administration has authorized sodium oligomannate for treating mild-to-moderate Alzhei...
Pharmacokinetics and tissue distribution of liposomal etoposide in rats. Drug Deliv. 2009;16(8):423-9.Sistla A, Smith DJ, Kobrinsky NL and Kumar K 2009 Pharmacokinetics and tissue distribution of liposomal etoposide in rats. Drug Deliv. 16 423–429...
In the study of the pharmacokinetics of TCM, the low concentration of components in the body, usually at the nanogram level, along with interference from endogenous substances, presents challenges for detection using conventional instruments. Chromatography-mass spectrometry technology is a widely utilized...
III. A study into the in vitro cutaneous delivery of vesicle-incorporated tretinoin. The influence of drug thermodynamic activity and niosome composition, size, lamellarity and charge on the (trans)dermal delivery of tretinoin (TRA) was stu... M Manconi,C Sinico,D Valenti,... - 《...
Pharmacokinetics is the discipline that quantifies the processes concerning the changes of drug concentrations within the body, whereas pharmacodynamics is the study of the biological response to a drug. Hence, the absorption, distribution, metabolism, and excretion of a drug are pharmacokinetic processe...
E. (1985) Pharmacokinetics, binding and distribution of Hoechst 33342 in spheroids and murine tumours. Br. J. Cancer 52 , 739–746.P. L. Olive, D. J. Chaplin, R E. Durand, Pharmacokinetics, binding and distribution of Hoechst 33342 in spheroids and murine tumors, Br. J, Cancer , 52...
The acquired data will provide useful information for the in vivo pharmacology of 8-acetamino-isocorydine, and can be applied to new drug research. Graphical abstract Pharmacokinetics and tissue distribution of isocorydine derivative 8-acetamino-isocorydine were investigated by HPLC-DAD coupling ...