and patients have so many different symptoms, mitochondrial diseases can be difficult to diagnose. There is no single laboratory or diagnostic test that can confirm the diagnosis of a mitochondrial disease. This is why referral to a medical facility wit...
There seems to be a strange chemistry in the bodies of certain people that produces a strong craving for alcohol. They start drinking it in normal manner with their food, or socially, but are unable to control themselves and go on to excess. Beer and whiskey were prob. unknown to the Jew...
The acute inflammatory process is a vital response to injury and infection that protects the organism against invading pathogens and repairs tissue damaged by trauma. Acute inflammation is self-limiting with a resolution phase that terminates the inflammatory response and initiates the reparative process ...
Since 1977, influenza A H1N1, influenza A H3N2, and influenza B viruses have been circulating worldwide. In the last century there have been three pandemics of influenza A that occurred in 1918, 1957, and 1968. The most devastating of these pandemics was the 1918 outbreak of “Spanish flu,...
P values were calculated with the hypergeometric test and corrected for multiple testing with the gprofiler-g:SCS. The tile plot shows enriched genes in each of the pathways. Blue, green and red represent the genes that contributed to the enrichment of Fgut, Faid and Falrg respectively. b ...
Medication.PrEP, which stands for pre-exposure prophylaxis, is a type of daily drug therapy that can prevent HIV infection. It's approved for people at very high risk who are negative for the virus. You may also be able to prevent infection with chlamydia, gonorrhea, or syphilis if you ge...
As a consequence of adaptive immune memory, if an infectious agent makes a second attempt to infect a host, pathogen-specific memory T cells, memory B cells, and antibodies will mount a secondary immune response that is much more rapid and intense than the initial, primary response and, thus...
This accepted paradigm is based on clinical evaluations that may not actually capture the breadth of the impact of a disease, which is especially true in the setting of complex, multisystem, rare diseases with small, extremely heterogeneous patient populations. The multi-domain responder index (MDR...
(PET) imaging data in humans, which confirmed that OS were enhanced in the motor cortex in ALS patients compared with controls. Moreover, the observed OS increase in the mild stage of the disease led to the conclusion that OS may be an important factor associated with the development of ...
The developing world, and in particular Latin America and the Caribbean (LAC), has experienced both a secular decline in mortality and significant improvements in the health of its population over the last 200 years. As we start the twenty-first century, a key observation is that the pattern ...