More and more associations to genetic predisposition are known. Objective Are there currently clinically relevant findings on the genetic predisposition to diseases of the lungs and respiratory tract? Methods Using the example of impaired mucociliary clearance, we explain the mechanisms of a monogenic ...
Occupational diseases of the airways, lungs and pleura notified according to chapter III of the List of occupational diseases accounted in 1996 to 2001 (2438 new cases) for 20% of all occupational diseases. The trend of occupational respiratory diseases was throughout the six-year interval declinin...
Emphysema slowly destroys the alveoli and the elastic fibers that hold open the small airways leading to the alveoli. It reduces the surface area of the lungs and the amount of oxygen that reaches the bloodstream. Tobacco smoking is the leading cause of this condition. Pulmonary edema is the a...
Small airways offer 1/4th of the total airways resistance. Disease of small airways results from exposure to tobacco smoke, mineral dust, air-pollutants, and viral infections. It may also be associated with connective tissue disorders or may follow bone marrow, lung, or heart-lung transplantation...
In this chapter we present a comprehensive review of less common pulmonary conditions, organized in an anatomic manner, and discuss, in order, the pulmonary vasculature, conditions that obstruct the airways, the pulmonary interstitium, and conditions extrinsic to the lungs that affect pulmonary ...
Lung Diseases Affecting the Airways Your windpipe (trachea) branches into tubes called bronchi, which in turn become smaller tubes throughout your lungs. Diseases that can affect these airways include: Asthma.Your airways are constantly inflamed and may spasm, causingwheezingand shortness of breath....
Lung Diseases Affecting the Airways Your windpipe (trachea) branches into tubes called bronchi, which in turn become smaller tubes throughout your lungs. Diseases that can affect these airways include: Asthma.Your airways are constantly inflamed and may spasm, causingwheezingand shortness of breath....
1. THE NORMAL CHEST . The Airways and Pulmonary Ventilation . The Pulmonary Vascular System . The Bronchial Circulation . Pulmonary Defense and Other Nonrespiratory Functions . Development and Growth of the Lung . Innervation of the Lung . The Pleura . The Lymphatic System . The Thoracic Inlet ...
The lungs are directly exposed to higher oxygen concentrations than most other tissues. Increased oxidative stress is a significant part of the pathogenesis of obstructive lung diseases such as asthma and chronic obstructive pulmonary disease, parenchymal lung diseases (e.g., idiopathic pulmonary fibrosis...
(ROS)inthelungsofaffectedindividualsarereflectedbyelevatedconcentrationsofoxidativestressmarkersinthebreath,airways,lungtissueandblood[1].Measurementofthesebiomarkershasinvolvedinvasiveprocedurestoprocurethesamplesortoexaminetheaffectedcompartments,tothepatient_sdiscomfort.Inducedsputum(IS),provingtobeasafeand...