More and more associations to genetic predisposition are known. Objective Are there currently clinically relevant findings on the genetic predisposition to diseases of the lungs and respiratory tract? Methods Using the example of impaired mucociliary clearance, we explain the mechanisms of a monogenic ...
Yourlungsare part of a complex system, expanding and relaxing thousands of times each day to bring in oxygen and send out carbon dioxide. Lung disease can happen when there are problems in any part of this system. Lung Diseases Affecting the Airways Your windpipe (trachea) branches into tubes...
reactiveoxygenspecies(ROS)inthelungsofaffected individualsarereflectedbyelevatedconcentrationsof oxidativestressmarkersinthebreath,airways,lung tissueandblood[1].Measurementofthesebiomarkers hasinvolvedinvasiveprocedurestoprocurethesamples ortoexaminetheaffectedcompartments,tothe ...
Diseases of the air space of the lung share many common findings and presentation that it makes more sense to be grouped together in a differential diagnosis. The common imaging finding is usually as a lung infiltrate or consolidation of some type of distribution or another. Trying to find the...
It happens when fluid seeps from blood vessels into the airways making breathing difficult. It is caused by either back pressure in the lungs as a result ofheartfailure or when a lung injury breaks blood vessels and causes them to leak. ...
It has been anecdotally said that there is an overlap in the timing of these stages due to asynchronous development of the lungs [18]. During all stages of endodermal development, the lung mesoderm (or mesenchyme) develops and interacts with the lung endoderm to promote branching and ...
Profound alterations of respiratory function and cardiovascular physiology accompany normal pregnancy in healthy women; these conditions contribute to many of the disorders of the lungs during pregnancy. The adaptive changes during the gravid period are designed to support maternal and fetal well-being dur...
We suggest that the influence of isoprenaline on maximal flows results from a bronchodilation, associated with an increased collapsibility of the central intrathoracic airways, whereas the influence of VC might reflect a delayed onset of small airway closure. 展开 ...
The lungs were long thought to be sterile until technical advances uncovered the presence of the lung microbial community. The microbiome of healthy lungs is mainly derived from the upper respiratory tract (URT) microbiome but also has its own characteri
It is closely related to human RSV, which often infects the airways of children. Both are single-stranded RNA enveloped viruses. In bovines, RSV causes respiratory infections in young animals and dairy cows. The virus is mainly present in the lower airways (the lobes of the lungs),...