Copper content was determined spectrographi cally in various portions of the brain in 10 healthy patients who died accidentally, in the brain of a patient with hepatolenticular degeneration, as well as in variou
As an important transition metal, Cu is present in nearly all living organisms. Extensive research has evinced that copper often acts as a cofactor for various metabolic enzymes and participates in the regulation of several physiological processes [15]. However, due to the metal toxicity of Cu, ...
In particular due to the increasing number of available interventional therapies in the carotid artery territory, significantly less attention has been given to the posterior circulation and therefore to vertebrobasilar infarctions. In many instances the described vascular system continues to be only insu...
Common STDs in women include chlamydia, gonorrhea, HPV, genital herpes, and the Zika virus. Sexually transmitted diseases (STDs) are infections that can be transferred from one person to another through any type of sexual contact. STDs are sometimes referred to as sexually transmitted infections (...
1.Wilson’s disease:It is caused due to the accumulation of copper in the liver, brain and other vital organs. 2.Gaucher’s disease:It is the result of a buildup of certain fatty substances in certain organs, particularly the spleen and liver. ...
113,114,115,116 This unique organelle traces its evolutionary origins to symbiotic bacteria, and while it functions in close cooperation with its host cell, it retains a degree of semi-autonomy due to its possession of mitochondrial DNA (mtDNA).117,118,119,120 This alternative genetic system, ...
Overproduced reactive oxygen and reactive nitrogen species (RONS) in the brain are involved in the pathogenesis of several neurological diseases, such as Alzheimer's disease, Parkinson's disease, traumatic brain injury, and stroke, as they attack neurons
This chapter addresses the basic biology, husbandry, and more common and important diseases of three ruminant species—sheep, goats, and cattle—commonly used in the laboratory. One chapter is simply not adequate, however, to address the many details and complexities of these species’ biology, ...
(RPE).99In addition, due to changes in heterochromatin, neurodegeneration-associated proteins are tightly related to the derepression of repetitive element transcription.100Saldi et al. reported that this derepression results in an elevation in the level of intracellular dsRNA, which activates innate ...
Moreover, recent evidence sug- gests that only certain subpopulations of MVBs fuse with plasma membrane due to the selective binding of sup- porting factors for plasma fusion [4, 31, 32]. After MVB fusion with the plasma membrane, ILVs are released into extracellular space, which are defined...