Parkinson disease (PD) 帕金森病is a degenerative condition退行性疾病 of the brain associated with motor symptoms (slow movement动作迟缓, tremor震颤, rigidity僵硬 and imbalance不平衡) and other complications including cognitive impairment认知障碍...
Organic Brain Disease in the FamilyMelvin R. Lansky
Parkinson disease (PD) 帕金森病is a degenerative condition退行性疾病 of the brain associated with motor symptoms (slow movement动作迟缓, tremor震颤, rigidity僵硬 and imbalance不平衡) and other complications including cognitive impairment认知障碍, mental health disorders精神障碍, sleep disorders睡眠障碍 and...
In the pre-ADHD era, when child sciences established themselves as academic fields of study and special education expanded quickly, brain-related psychiatric labels like “minimal brain damage” (MBD, later “dysfunction”) were often used for inattentive or hyperactive children. These diagnoses seem...
a German doctor. In 1906, Dr. Alzheimer noticed changes in the brain tissue of a woman who had died of an unusual mental illness. He found abnormal clumps. Scientists also have found other brain changes in people with AD. Nerve cells die in a...
Correspondence: kunikazu@cc.hirosaki-u.ac.jp 1Department of Neuropathology, Institute of Brain Science, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki 036-8562, Japan Full list of author information is available at the end of the article protein degradation in the brain....
1Alzheimer's disease is (1) brain disorder that causes problems with memory, thinking and behaviour.If someone has several or even most of the signs (2) (list) above, it does not mean that he has Alzheimer's disease. (3) , it is important to consult a health care provider. The majo...
This membrane is produced by expansions of specialized glial cells of the brain, "the mature oligo- dendrocytes", derived from oligodendrocytes progenitor cells (OPCs) [21]. This cell line constitutes the precursor cells for the constitution of the myelin sheath through a well-defined program ...
Alzheimer’s disease (AD) is the most common neurodegenerative disease that currently lacks available effective therapy. Thus, identifying novel molecular biomarkers for diagnosis and treatment of AD is urgently demanded. In this study, we exploited tools and concepts of the emerging research area of...
Journal of Neuroinflammation (2023) 20:208 https://doi.org/10.1186/s12974-023-02879-7 Journal of Neuroin ammation RESEARCH Open Access H3K18 lactylation of senescent microglia potentiates brain aging and Alzheimer's disease through the NFκB signaling pathway Lin Wei1,2†, Xiao...