Due to the differences in human and mouse NLRP1, much of the recent literature focuses on human NLRP1 inflammasome formation and function. As more studies explore the mechanisms underlying NLRP1 activation, dysfunction of this unique NLR has become implicated in a rapidly expanding range of infecti...
The proportion of malnutrition due to intensely reduced bile acid-dependent absorption of fats and fat-soluble nutrients is, however, difficult to quantify compared to that caused by fibrosis/cirrhosis per se. Chronic enteropathy secondary to associated portal hypertension, poor nutrient intake, ...
the disease may be caused by some agent external to the organism, such as a chemical that is atoxicagent. In this case the disease is noncommunicable; that is, it affects only the individual organism exposed to it. The external agent may be itself a living organism capable of multiplying ...
Chronic obstructivepulmonary disease(COPD) is a generic term encompassing several different disease processes that causeairways obstructionthat is not fully reversible. Except for disease due to inherited deficiency of α1-antitrypsin and inherited and acquired disorders causingbronchiectasis, COPD is closely...
Continuous cultivationFusarium oxysporumpotassium deficiencyroot exudatesstrawberryStrawberry fruits are increasingly produced underZeng-Qiang CaoTeng-Fei FanYan-Meng BiGei-Lin TianLu-Sheng ZhangNew Zealand Journal of Crop and Horticultural Science
Pot and tissue culture grown strawberry (Duch) plants were used to determine the effect of strawberry root exudates on the growth of strawberry plants and under continuous cultivation and potassium (K) deficiency. The pot experimental results showed that the Fusarium wilt disease rating and index ...
consistent with a quantitative reduction of the entire CI in affected cells (Supplementary Fig.S1). Subunit NDUFS4 was chosen for downstream analyses due to superior staining quality. Neuronal CI status was subsequently assessed, along with the total mitochondrial mass marker VDAC1, in the dopaminer...
The concept of cell death has been expanded beyond apoptosis and necrosis to additional forms, including necroptosis, pyroptosis, autophagy, and ferroptosis. These cell death modalities play a critical role in all aspects of life, which are noteworthy fo
The realization that autoantibodies can contribute to dysfunction of the brain has brought about a paradigm shift in neurological diseases over the past decade, offering up important novel diagnostic and therapeutic opportunities. Detection of specific a
The three major forms of GM2 gangliosidosis include Tay–Sachs disease and its variants due to a HEX A deficiency (also known as the B types); Sandhoff disease with a deficiency of both HEX A and HEX B (also called the O type); and the AB variant caused by an abnormality of ...