Mitochondria-endoplasmic reticulum contacts (MERCs), also called endoplasmic reticulum (ER)-mitochondria contact sites (ERMCS), are the membrane domains, where these two organelles exchange lipids, Ca2 ions, and reactive oxygen species. This crosstalk is a major determinant of cel...
Mitochondria frequently change their morphology by fusion and fission, and these dynamic morphologic changes are essential for maintaining both mitochondrial and cellular functions. The cytoplasmic dynamin-related guanosine triphosphatase (GTPase) Drp1 (Dnm1 in yeast) is recruited to mitochondrial fission sit...
A new chimeric gene, orfH79, was found in the region. OrfH79 had homology to mitochondrial gene cox II and orf107, and was special to HL-sterile cytoplasm. 展开 关键词: cytoplasmic male sterility mitochondria chimeric gene.DOI: 10.1360/02TB9168 年份: 2002 ...
Hypopharyngeal carcinoma (HC), which accounts for approximately 3% of all head and neck cancers [1], is a relatively rare type of cancer. The main pathological type is squamous cell carcinoma [2], and the common level of differentiation is low. The overall five-year survival rate for hypopha...
Observational and experimental discoveries of new factual entities such as objects, systems, or processes, are major contributors to some advances in the l
(2 peptides), showed a high likelihood of being targeted to the mitochondria while the respective canonical proteins have cytosolic or nuclear location (Supplementary Data6). This result suggests that, for certain genes, the existence of an upstream TIS in the same reading frame as the canonical...
No surface folds of mast cell took part in its formation. No mitochondria and vesicles appeared in the terminal. No Schwann cell ensheathed the axon terminal. Schwann cell were found accompanying A-type junction. They envelop- ed the axon terminal and could set up close contact with mast ...
The first of these compounds, SS-31, is currently in multiple clinical trials. Clinical Pharmacology & Therapeutics (2014); 96 6, 672–683. doi 展开 关键词: Humans Mitochondria Burns Insulin Resistance Cytochromes c Adenosine Triphosphate Oligopeptides Cardiolipins Energy Metabolism Aging DOI: 10.1038...
& Juez, G. Biological significance of a family of regularly spaced repeats in the genomes of Archaea, Bacteria and mitochondria. Mol. Microbiol. 36, 244–246 (2000). Article CAS PubMed Google Scholar Makarova, K. S., Aravind, L., Grishin, N. V., Rogozin, I. B. & Koonin, E. ...
particularly in some peripheral nerves whose axons extend from several centimeters long to even up to a meter. Mitochondria function as powerhouses to generate ATP. Efficient long-distance mitochondrial mobilization and transport, which are driven by microtubule (MT)-based motors, is critical for neur...