In all cases though, drugs interact at the molecular level with either the cell type or tissue in the body affected by and/or causing the disease; in the case of an infectious disease they may also kill the responsible microorganism or virus, eliminating it from the body to exert a ...
6 Zhong, C.et al.Parthenogenetic haploid embryonic stem cells efficiently support mouse generation by oocyte injection.Cell Research26, 131-134, doi:10.1038/cr.2015.132 (2016). 7 Li, Z.et al.Birth of fertile bimaternal...
5 Li, L. et al. Single-Cell RNA-Seq Analysis Maps Development of Human Germline Cells and Gonadal Niche Interactions. Cell Stem Cell 20, 858-+, doi:10.1016/j.stem.2017.03.007 (2017). 6 Tang, W. W. C. et al....
2024年3月29日,浙江大学基础医学院/良渚实验室钱鹏旭研究员团队在Cell Discovery上发表了题为“Microplastics Dampen the Self-renewal of Hematopoietic Stem Cells by Disrupting the Gut Microbiota-Hypoxanthine-Wnt Axis”的研究论文,该研究通过构建小鼠微塑料模型,证明长期摄入微塑料可对HSCs的数目与功能造成严重的损害。
By contrast, the stem cells model suggests that cancer heterogeneity is due to the hierarchy that originates from a small population of cancer stem cells (CSCs) which are biologically distinct from the bulk tumor and possesses self-renewal, tumorigenic and multilineage potential. Although these two...
Naturally occurring stem cells isolated from humans have been used therapeutically for decades. This has primarily involved the transplantation of primary cells such as haematopoietic and mesenchymal stem cells and, more recently, derivatives of pluripot
今天,我们特别介绍一项张教授于2022年10月11日发表在《Cell Discovery》的近期研究——Generation of high-performance human cardiomyocytes and engineered heart tissues from extended pluripotent stem cells,该研究利用人扩展多能干细胞(EPSC)诱导出心肌细胞,并测试了这种新型来源的心肌细胞的性能,为心脏相关研究提供了...
Therefore, it may be more appropriate to describe the majority of NCCs as progeni- tor cells rather than true stem cells [4]. Progenitor cells like stem cells have the capacity to self-renew and dif- ferentiate, but in contrast to stem cells both capacities are more limited. Despite these...
今天,我们特别介绍一项张教授于2022年10月11日发表在《Cell Discovery》的近期研究——Generation of high-performance human cardiomyocytes and engineered heart tissues from extended pluripotent stem cells,该研究利用人扩展多能干细胞(EPSC)诱导出心肌细胞,并测试了这种新型来源的心肌细胞的性能,为心脏相关研究提供了...
6. Morton J, Hutchins C, Durrant S:Granulocyte–colony-stimulating factor (G-CSF)–primed allogeneic bone marrow: significantly less graft-versus-host disease and comparable engraftment to G-CSF–mobilized peripheral blood ...