The validation cohort included 154 cases and 154 controls from a random population-based selection of 5,815 patients. Our approach enabled the collection of a large number of early-stage melanoma samples from population-based databases with extensive follow-up and a sufficient number of metastatic ...
Develop and validate gene expression–based biomarker associated with recurrent disease to facilitate risk stratification of clear cell renal cell carcinoma (ccRCC).#We retrospectively identified 110 patients who underwent radical nephrectomy for ccRCC (discoverycohort). Patients who recurred were matched on...
Helicobacter pylori Eradication Therapy Is Not Associated With Increased Risk of Cardiovascular Mortality, Based on a National Cohort Study Gastro Hep Advances, Volume 1, Issue 1, 2022, pp. 25-28 S.C. Shah,…, C.L. Roumie View PDFShow 3 more articles Article Metrics Captures Readers12 View...
A validation study of a new classification algorithm to identify rheumatoid arthritis using administrative health databases: case–control and cohort diagn... OBJECTIVES: To develop and validate a new algorithm to identify patients with rheumatoid arthritis (RA) and estimate disease prevalence using admin...
Validation of the autophagy-related signature via an independent cohort We calculated the risk score for each patient in the GEO dataset GSE27020 as an independent external validation using the same formula. The patients were divided into high-risk and low-risk groups based on the median risk sco...
IntroductionThe SPIN (Sant Pau Initiative on Neurodegeneration) cohort is a multimodal biomarker platform designed for neurodegenerative disease research following an integrative approach.doi:10.1016/j.trci.2019.09.005John Wiley & Sons, LtdAlzheimer's & Dementia: Translational Research & Clinical ...
Fourth, we show that the blood levels of SAT1 (spermidine/spermine N1-acetyltransferase 1), the top biomarker identified by us, at the time of testing for this study, differentiated future as well as past hospitalizations with suicidality, in a live cohort of bipolar disorder subjects, and ...
These patient cohorts will be compared to well characterized samples from a population-based cohort study (the Study of Health in Pomerania; SHIP) in a case-control setting. One important aspect of t ... 展开 关键词: Prostate Cancer Prostatitis Mean Corpuscular Volume Protein Microarray Stable ...
Mass-spectrometry-based proteomic analysis is a powerful approach for discovering new disease biomarkers. However, certain critical steps of study design such as cohort selection, evaluation of statistical power, sample blinding and randomization, and sa
Intraocular retinoblastoma treatment has changed radically over the last decade, leading to a notable improvement in ocular survival. However, eyes that re