A recent analysis, 23 years after the closure of the plant provides new insights in cancer mortality and dose-response relationships for the exposed cohort (Manuwald et al. 2012). In the light of these findings there is a need to critically review the current convention of 200 ppt 2,3,7...
toxiques générés par le fonctionnement de ce système de défense (par exemple les intermédiaires réactifs potentiellement génotoxiques) induiraient plutôt une toxicité sur le long terme en raison d’abord de leur fugacité et du type d’effets toxiques produits comme le cancer. On...
A composition for preventing and treating cancer such as skin cancer comprises dibenzo-p-dioxine derivatives represented by the formulae(1) to (10), wherein R is H, acetyl group, oleoyl group or methyl group, and is formulated as capsule or tablet, wherein the daily dosage of the ...
To provide therapeutic agents for treatment and/or prevention of proliferative diseases, such as cancer.SOLUTION: The invention provides a compound represented by a formula IA. (Rand Rare each independently selected from hydrogen, fluoro, chloro, cyano, (1-2C)alkyl, (1-2C)alkoxy, (1-2C)...
Compounds and compositions comprising compounds that modulate pyruvate kinase M2 (PKM2) are described herein. Also described herein are methods of using the compounds that modulate PKM2 in the treatment of cancer.doi:EP2448582 A1SAUNDERS JeffreySALITURO Francesco G.YAN ShunqiEP...