Pharmacokinetic interactions have been observed and reported primarily when digoxin is coadministered by oral route. There are very few studies that have evaluated the drug interaction when digoxin is administered via IV route. The magnitude of digoxin exposure change through IV route is generally lower...
lenta as the sole microbe known to carry out the conversion of digoxin to dihydrodigoxin in isolation (Fig. 2a) [48]. The case of digoxin metabolism by E. lenta is especially interesting not only for the clinical relevance of the biotransformation, but because it is one of the few ...
When switching from intravenous to oral digoxin formulations, make allowances for differences in bioavailability when calculating maintenance dosages (see Table 6). Table 6: Comparison of the Systemic Availability and Equivalent Doses of Oral and Intravenous LANOXIN ...
Pharmacokinetic interactions have been observed and reported primarily when digoxin is co-administered by oral route. There are very few studies that have evaluated the drug interaction when digoxin is administered via IV route. The magnitude of digoxin exposure change through IV route is generally low...
= 125 mcg oral tab/solution heart failure w/ reduced ejection fraction [premature neonates] Dose: 4.7-7.8 mcg/kg/day (solution) PO divided q12h; Alt: 3.8-6.2 mcg/kg/day IM/IV divided q12h; Info: may load 20-30 mcg/kg (solution) PO or 15-25 mcg/kg IM/IV, divided into 3 doses...
a) What are the effects of Coumadin anticoagulants on the clotting mechanism? b) How do they work? c) What laboratory test can be used to monitor the effect of the anticoagulant? Tick the drug used as an oral anticoagulant: a. Heparin b. Dalteparin c. Dicumarol d. Enoxapar...