Based on data from two lactation studies in a total of 13 breastfed infants, the digoxin concentrations in breast milk were between 0.4 – 1.0 ng/mL following 0.25 mg once daily dose of digoxin in the lactating mother. Thus, the amount of digoxin ingested daily by the infants is estimated...
SODIUM PHOSPHATE, DIBASIC, ANHYDROUS (UNII: 22ADO53M6F) 3 mg in 1 mL ANHYDROUS CITRIC ACID (UNII: XF417D3PSL) 0.8 mg in 1 mL WATER (UNII: 059QF0KO0R) CITRIC ACID MONOHYDRATE (UNII: 2968PHW8QP) SODIUM PHOSPHATE (UNII: SE337SVY37) Packaging #Item CodePackage DescriptionMarke...
The coadministration of 50 mg/kg quercetin unexpectedly resulted in sudden death of two among three pigs within 30 min after digoxin administration. The coadministration of 40 mg/kg quercetin significantly elevated the C max of digoxin by 413% and increased the AUC 0-t by 170%. The results...
Each subject received daily oral doses of digoxin 0.25 mg on Days 1 through 13 during both treatment periods. Aprepitant 125 mg (or matching placebo) was coadministered orally with digoxin on Day 7, and aprepitant 80 mg (or matching placebo) was coadministered orally with digoxin on Days 8...
Supplementary Material (0) References (13) Grollman A (1929) Physiological variations in the cardiac output of man. III The effect of ingestion of food on the cardiac output pulse rate, blood pressure and oxygen consumption of man. Am J Physiol 89: 366–370 Figueras J, Singh BN, Ganz...
Table 5: Time-dependent sex–digoxin interactions Interaction p value 0·0179 0·0076 0·13 0·96 propensity for baseline digoxin use, and time-dependent adjustment for digoxin use during the study. Additionally, we noted no significant digoxin–heart failure interaction for all-cause mortality, ...
v. at a dose of 480 mg. Serum free-digoxin concentration fell within half an hour to 0, with simultaneous rise of total digoxin from 13 μg/l to a maximum of 176 μg/l after 2 hours. At the same time there was marked improvement in the clinical condition with restoration of a ...
After treatment, programmed stimulation initiated ventricular tachyarrhythmias in only 1 of 13 digoxin-treated dogs (1.36 卤 0.17 ng/ml serum digoxin) and in 0 of 13 vehicle-treated dogs. However, the incidences of early ventricular fibrilation (4 of 10 digoxin vs 0 of 12 vehicle;p < 0.05...
Digoxin levels in various fluids and tissues were estimated by radioimmunoassay: bloodplasma 20–25ng/ml, liquor 10–13 ng/ml, liver 100–110ng/g, kidney 130–145 ng/g; the gastric fluid contained 0,6 mg. Forensic aspects of glycosid-intoxication, especially of the varying concentrations in...
Kayali F, Janjua MA, Laber DA, Miller D, Kloecker G. 2011. Phase II trial of second-line erlotinib and digoxin for nonsmall cell lung cancer (NSCLC). Open Access Journal of Clinical Trials 3:9-13. DOI: https://doi.org/10.2147/ OAJCT.S16347...