In diffuse-type GC, differentiation is relatively poor, and the probability of distant metastasis and lymph node metastasis is high, resulting in poor clinical prognosis. The purpose of this study was to identify specific genes that can predict the prognosis of different types of GC. Differentially...
BackgroundMechanistic target of rapamycin (mTOR) pathway is essential for the growth of gastric cancer (GC), but mTOR inhibitor everolimus was not effective for the treatment of GCs. The Cancer Genome Atlas (TCGA) researchers reported that most diffuse-type GCs were genomically stable (GS). ...
Gastric cancer (GC) is the third leading cause of cancer mortality in the world, particularly in East Asia, which accounts for more than half of the cases worldwide1, 2. GC is heterogeneous at the genetic and cellular levels3. The Lauren classification stratifies GC into diffuse, intestinal...
Moreover, mestranol could significantly suppress tumour growth of the GC cells subcutaneously transplanted into nude mice, consistent with longer survival time in the female DCKO mice than in the male. Expectedly, human E-cadherin-mutant and -low gastric cancer cells showed higher susceptibility to ...
Tenosynovial giant cell tumors (GCTs) typically form in the joints or extra-articular soft tissues such as the tendon sheath, and are benign tumors that commonly occur in the hands or wrists in the third to fifth decades of life. However, the diffuse type of extra-articular GCT arising wit...
We studied DNA copy number changes in gastric cancer (GC) using comparative genomic hybridization (CGH) analysis on 35 resected gastric carcinomas (22 of t... A Kokkola,O Monni,P Puolakkainen,... - 《Genes Chromosomes & Cancer》 被引量: 227发表: 1997年 Cytogenetic and molecular aspects ...
(DLBCL)ofsofttissuewasmade.ThesubtypeofDLBCLisnon-germinalcentertype(non-GC).Systemic investigationusingvariousimagingmodalitiesincludingCT,MRIandGa-scintigraphyrevealedsmall nodularlesionsupto1mminthelungsandliver.However,biopsiesoftheselocationswerenotperformed ...
Collectively, these data identify high and preferentially nuclear protein expression of ATF3 as a hallmark of human non-GC/ABC DLBCL. Figure 5. Strong nuclear ATF3 expression is a hallmark of non-GC and ABC DLBCL patients. (A) Relative mRNA expression of ATF2, ATF3, and ATF7 in ABC vs...
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There are eight catechins: C ((-)-catechin), EC ((-)-epicatechin), ECG ((-)-epicatechingallate), EGC ((-)-epigallocatechin), EGCG ((-)-epigallocatechin gal- late), GC ((-)-gallocatechin), CG ((-)-catechingallate), and GCG ((-)-gallocatechingallate) [98]. Flavanols are found ...