This study demonstrated that damage to the cerebral microvasculature, the formation of microthrombi and swelling of vascular endothelial cells occur early and peak 12 hours after injury in a rat model of diffuse axonal injury. Moreover, these pathological changes were most evident in the cerebral ...
Traumatic axonal injury has consistently been reported to activate microglia and inflammatory pathways, both in animal models as well as in human TBI22,55,56, and elevations of pro-inflammatory cytokines and chemokines are observed in serum, CSF and in brain interstitial fluid56. In human brain t...
A preliminary study in 6 cases with neuroradio- logical features consistent with diffuse axonal injury. Acta Neurochir (Wien) 149:347-356Haemodynamic patterns in children with posttraumatic diffuse brain swelling. A preliminary study in 6 cases with neuroradiological features consistent with diffuse ...
International Journal of Molecular Sciences Review Diffuse Axonal Injury and Oxidative Stress: A Comprehensive Review Alessandro Frati 1,2, Daniela Cerretani 3, Anna Ida Fiaschi 3, Paola Frati 1,4, Vittorio Gatto 4, Raffaele La Russa 1,4 ID , Alessandro Pesce 2, Enrica Pinchi 4, Alessandro ...