Nishioka, Selection of human cells having two different types of mutations in individual cells (genetic/artificial mutants): Application to the diagnosis of the heterozygous state for a type of adenine phosphoribosyltransferase deficiency., Hum. Genet. 76: 148 (1987). View Article...
题目Face Shape Lets Al Spot Rare DisordersPeople with genetic syndromes (综合征) sometimes have revealing facial features, but using them to make a quick and cheap diagnosis can be 1 given there are hundreds of possible conditions they may have. A new neural (神经系统...
Population Geneticist Selection, mutation, migration, genetic drift Multigenerational change in allele or genotype frequency, polymorphism, heterozygosity Molecular Evolutionist or Phylogenetic Systematicist Evolutionary tree of changes in DNA sequence A traceable molecular character inherited by all progeny ...
A simple blood test detects eight different kinds of cancer by looking for genetic mutations and proteins linked with tumours.doi:10.1038/d41586-018-00926-5Heidi LedfordNatureSimple Blood Test Detects Eight Different Kinds of Cancer, Nature. 18 January 2018. Available online: https://www.nature....
Genetic Mutations in jamb, jamc, and myomaker Revealed Different Roles on Myoblast Fusion and Muscle GrowthJambJamcMyomakerMuscle fusionZebrafishMyoblast fusion is a vital step for skeletal muscle development, growth, and regeneration. Loss of Jamb, Jamc, or Myomaker (Mymk) function impaired myoblast...
Candidate genes thus identified can be selected for further reverse genetic analysis. To date, genome-wide transcriptome analysis of dry stigmas has been conducted in Arabidopsis, rice, and maize [11–15]. The Arabidopsis stigma dataset was established by cDNA subtraction and microarray analysis of...
Although the accumulation of random genetic mutations has been traditionally viewed as the main cause of cancer progression, altered mechanobiological prof... Sevgi Onal,Maan M. Alkaisi,Volker Nock - Heliyon 被引量: 0发表: 2025年 This invention relates to the intimate commixing of coarsely pre-...
Common alterations of cell cycle control (i.e. TP53, CDKN2A/RB1 mutations), oxidative stress (i.e. NFE2L2/KEAP1/CUL3), cell survival (i.e. genes in the Pi3K/Akt pathway), cell differentiation (i.e. SOX2/TP63/NOTCH1) and epigenetic (i.e. KMT2C, KMT2D) pathways are also ...
(75.2% vs. 61.7%, respectively). Such studies denote the importance of detecting the contributing genes to breast cancer and utilizing appropriate therapeutic agents for the disease treatment20. Genetic studies have revealed the most critical anti-oncogenes and oncogenes that are related to breast ...
Over the past decade, there have been major breakthroughs in the understanding of inherited causes of congenital heart disease, including the identification of specific genetic abnor- malities for some types of malformations (2). Additionally, a growing body of epidemiological literature has shown ...