Orphanet Journal of Rare DiseasesMauri L, Uebe S, Sticht H, Vossmerbaeumer U, Weisschuh N, Manfredini E, Maselli E, Patrosso M, Weinreb RN, Penco S, et al: Expanding the clinical spectrum of COL1A1 mutations in different forms of glaucoma. Orphanet J Rare ...
These disorders are also associated with different ocular abnormalities, although recognition of the common pathology for both features is seldom being recognized. Our results expand the role ofCOL1A1mutations in different forms of early-onset glaucoma with and without signs of OI. Thus, we suggest...
The prostaglandin analogs are new exciting drugs added to the therapeutic armamentarium for patients with glaucoma. Several studies have evaluated the ocular hypotensive properties and side effects of latanoprost in different forms of glaucoma. This drug, seems to be the most effective intraocular pressur...
23. Consequently, inhibition of Grp94 holds promise as a therapy to treat myocilin-associated glaucoma21,22,23,25by preventing its toxic gain-of-function—accumulation in cells—as the absence of myocilin in humans26or mice27does not lead to glaucoma....
Necroptosis and pyroptosis are two forms of programmed cell death with a common feature of plasma membrane rupture. Here we studied the morphology and mechanism of pyroptosis in comparison with necroptosis. Different from necroptosis, pyroptosis undergoe
Should the wick run out of liquid it will burn and create that unpleasant bitter taste in your mouth. Trick: Always ensure that your wick does contain sufficient liquid. Medical Marijuana Edibles Marijuana edibles refer to all the edible forms(infused foods and beverages) in which marijuana ...
each person’s retina is unique. The network of blood vessels in the retina is so complex that even identical twins do not share a pattern. Although retinal patterns may be altered in cases of diabetes, glaucoma or retinal degenerative disorders, the retina typically remains unchanged from birth...
Yao, "A detailed meta-analysis shows no association between TNF-𝛼-308G/A polymorphism and different forms of glaucoma," Ophthalmic Research, vol. 47, no. 1, pp. 47-51, 2011.Yu QQ, Yao Y. A detailed meta-analysis shows no association between TNF-alpha-308G/A polymorphism and ...
In the stratified analysis by ethnicity and source of control subgroups, a significant association was still not observed in all genetic models. Conclusion: Our meta-analysis provides strong evidence that the TNF-α -308G/A polymorphism is not associated with different forms of glaucoma risk. ...
These collective findings suggest that ROCKs may be promising therapeutic targets for the treatment of these ROCK involved diseases. In fact, ripasudil, a pan-ROCK inhibitor (pan-ROCK-i) has been available as a new option of a hypotensive medication for patients with glaucoma and ocular ...