ain lighters known heretofore these means take the form of exposed latches and interior springs and levers which take up space in the lighters and reduce their storage capacity for inflammable lighter fluid 在此以前知道这些手段的打火机采取在打火机占去空间并且减少他们的存储容量为易燃的火机油被暴露的...
A second major difference between A-form and B-form nucleic acid is the placement of base-pairs within the duplex. In B-form, the base-pairs are almost centered over the helical axis but in A-form, they are displaced away from the central axis and closer to the major groove. The resul...
The majority of cases with an ±-thal-1 defect have a deletion of at least 18.1 kb starting 3 to the 1 gene which includes the ± and the two a genes; it is similar to that described in Thais. However, two families had a deletion of the entire -± gene cluster, i.e. -±-thal...
[Relationship of the I/D-polymorphism of the ACE gene and the T174M-polymorphism of the AGT gene to diabetic microangiopathies in children and adolescents] The purpose of the study was to examine a role of candidate genes of the renin-angiotensin system in the development of microangiopath...
The disruption of normal cleavage to produce secreted LCCL domain fragments and the tendency to form aggregations of mutant cochlins were tested byin vitrocell experiments. The two families showed different clinical symptoms. Family #32 was identified as having early-onset, progressive sensorineural ...
genes encoding DNA methyltransferase 3 alpha (DNMT3A), tet methylcytosine dioxygenase 2 (TET2), additional sex combs like 1 (ASXL1), Janus kinase 2 (JAK2) and tumor protein p53 (TP53)1. AmongJAK2mutations in CH,JAK2V617Fis the most common and can lead to uncontrolled expansion of HSCs ...
F-box proteins are substrate-recognition components of the Skp1-Rbx1-Cul1-F-box protein (SCF) ubiquitin ligases. In plants, F-box genes form one of the largest multigene superfamilies and control many important biological functions. However, it is unclear how and why plants have acquired a lar...
Histone genes in sea urchins are organized into a repeat unit of DNA with a modal length of 6-7 kilobases. Since all five histones are encoded in the unit, it is possible that a large initial transcript containing the sequences of the complete repeat is cleaved into 9S histone mRNAs. We...
Three circles represent the sets of genes that are specific to American, Asian and European races, respectively. Genes in the overlap of circles indicate that they are specific to multiple races. A total of ten genes are specific to only one race, whereas eight genes are specific to two ...
largely independent of which α2δ subunit is used. By contrast, mutations of some α2δ subunit genes cause brain disease, rendering functional redundancy unlikely a general scenario in vivo. Although some brain parts co-express multiple α2δ subunits28, differential spatial expression of α2δ...